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Comparative study of GC-MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils

dc.contributor.authorCarrasco, Alejandro
dc.contributor.authorTomas, Virginia
dc.contributor.authorTudela, José
dc.contributor.authorMiguel, Maria Graça
dc.date.accessioned2017-04-07T15:57:40Z
dc.date.available2017-04-07T15:57:40Z
dc.date.issued2016-07
dc.description.abstractThe chemical compositions of essential oils of Lavandula angustifolia, Lavandula latifolia, Lavandula hybrida cultivar Grosso and cultivar Super, Thymus zygis with high proportions of thymol and linalool and Thymus hyemalis, from Murcia country (Spain), were studied in relative (%), absolute (mM) and chiral concentrations by GC/MS. Hyaluronidase inhibition and antioxidant activities of the essential oils were evaluated using ABTS(center dot+), DPPH center dot, ORAC, chelating power, hydroxyl radical, nitric oxide, TBARS and reducing power assays. Linalool and linalyl acetate were the most abundant components in the Lavandula genus whereas thymol, linalool and 1,8-cineole were the most abundant molecules in the respective Thymus species. Chiral determination of the main components showed (+)-enantiomers like terpinen-4-ol, beta-pinene, borneol and a-terpineol and (-)-enantiomers like linalool, linalyl acetate and camphene in Lavandula sp. In the case of Thymus sp. (+)-enantiomers like a-pinene, limonene, terpinen-4-ol and a-terpineol and (-)-enantiomers like borneol were found. Essential oils containing thymol were found especially powerful in all assays but chelating power, ORAC and hydroxyl radical scavenging assays. The capacity for inhibiting hyaluronidase showed that T. zygis with a high proportion of thymol was the most effective inhibitor. Essential oils containing thymol and linalool/linalyl acetate have a potential use as antioxidant agents. Thymol shows strong inhibition of hyaluronidase. Copyright (C) 2015 John Wiley & Sons, Ltd.
dc.identifier.doi10.1002/ffj.3283
dc.identifier.issn0882-5734
dc.identifier.otherAUT: MGM00322;
dc.identifier.urihttp://hdl.handle.net/10400.1/9782
dc.language.isoeng
dc.peerreviewedyes
dc.publisherWiley
dc.relation.isbasedonWOS:000368256000006
dc.titleComparative study of GC-MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage69
oaire.citation.issue1
oaire.citation.startPage57
oaire.citation.titleFlavour and Fragrance Journal
oaire.citation.volume31
person.familyNameMiguel
person.givenNameMaria da Graça
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.orcid0000-0003-2507-4228
person.identifier.scopus-author-id35562054500
rcaap.rightsopenAccess
rcaap.typearticle
relation.isAuthorOfPublication2507350f-9e60-4d4a-a096-53e58d93549c
relation.isAuthorOfPublication.latestForDiscovery2507350f-9e60-4d4a-a096-53e58d93549c

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