Possible role of mycotoxins, malnutrition and MECP2 dysregulation in nodding syndrome

Catamo Vaz, Deise Haua da Silva; Costa, Maria Helena da; Buque, Helena Agostinho; Nzwalo, Hipólito

http://hdl.handle.net/10400.1/26117

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
1-s2.0-S0022510X24003976-main.pdf		452.32 KB	Adobe PDF	Download

Send Feedback

Authors

Catamo Vaz, Deise Haua da Silva

Costa, Maria Helena da

Buque, Helena Agostinho

Nzwalo, Hipólito

Abstract(s)

We read with great interest the manuscript by Spencer et al. [1] suggesting a possible role of Methyl-CpG-binding protein 2 (MECP2) dysregulation in the pathogenesis of Nodding syndrome (NS), a childhood onset epileptic disorder occurring exclusively in sub-Saharan Africa. The sociodemographic and phenotypic overlap of NS with MECP2 duplication syndrome, namely the age of onset interval, female predominance;