Non-ketotic hyperglycaemia induced occipital reflex focal seizures

Buque, Helena; Catamo, Deise; Felix, Catarina; André, Ana; Gil, Inês; Nzwalo, Hipólito

Publication

Non-ketotic hyperglycaemia induced occipital reflex focal seizures

2023-07Journal article

dc.contributor.author	Buque, Helena
dc.contributor.author	Catamo, Deise
dc.contributor.author	Felix, Catarina
dc.contributor.author	André, Ana
dc.contributor.author	Gil, Inês
dc.contributor.author	Nzwalo, Hipólito
dc.date.accessioned	2023-09-22T17:06:40Z
dc.date.available	2023-09-22T17:06:40Z
dc.date.issued	2023-07
dc.description.abstract	A myriad of neurological manifestations can occur in association with ketotic and non ketotic hyperglycaemic states. Contrary to diabetic coma, which is a universal complication under relatively established metabolic circumstances, the pathophysiology beyond hyperglycaemicassociated positive neurological manifestations, including seizures, remains to be elucidated. The occurrence of symptomatic focal epilepsy as a manifestation of diabetes-related hyperglycaemia is seldom reported. Herein, we present a case of focal epilepsy with alternating positive and negative neurological manifestations as the initial manifestation of diabetes-related hyperglycaemia. The electroencephalogram confirmed the diagnosis of focal occipital seizures, and the brain magnetic resonance imaging depicted the associated typical transient imaging findings in the occipital lobe. Seizures were refractory to antiepileptics, and symptomatic control was achieved after achieving normoglycemia. On follow-up, complete clinical and imaging recovery occurred. Reflex focal epilepsy in the context of hyperglycaemic states is a rare condition, and the possibility of misdiagnosis is likely high. As reported in similar cases, seizures can be resistant to antiepileptics. An important message to highlight is that seizures associated with hyperglycaemic status can be resistant to antiepileptic treatment and only cease with glycaemic control.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.doi	10.1016/j.heliyon.2023.e18355	pt_PT
dc.identifier.eissn	2405-8440
dc.identifier.uri	http://hdl.handle.net/10400.1/20012
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Elsevier	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Focal seizures	pt_PT
dc.subject	Hyperglycaemic states	pt_PT
dc.subject	Transient brain signs	pt_PT
dc.title	Non-ketotic hyperglycaemia induced occipital reflex focal seizures	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.issue	7	pt_PT
oaire.citation.startPage	e18355	pt_PT
oaire.citation.title	Heliyon	pt_PT
oaire.citation.volume	9	pt_PT
person.familyName	Buque
person.familyName	Catamo Vaz
person.familyName	André
person.familyName	Nzwalo
person.givenName	Helena Agostinho
person.givenName	Deise Haua da Silva
person.givenName	Ana
person.givenName	Hipólito
person.identifier	337064
person.identifier.ciencia-id	7D1E-BCB3-86E1
person.identifier.ciencia-id	E11E-315B-E8F5
person.identifier.ciencia-id	2C1F-E4F3-2C79
person.identifier.orcid	0000-0003-0359-9904
person.identifier.orcid	0000-0003-1921-4095
person.identifier.orcid	0000-0002-1502-3534
person.identifier.rid	AAG-3931-2020
person.identifier.scopus-author-id	36057285600
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT
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