Diels–Alder reactions of 3-(1H-tetrazol-5-yl)-nitrosoalkenes: synthesis of functionalized 5-(substituted)-1H-tetrazoles

Lopes, Susana M. M.; Palacios, Francisco; Lemos, A.; Melo, Teresa M. V. D. Pinho e

http://hdl.handle.net/10400.1/1046

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Tetrahedron 2011.pdf		872.46 KB	Adobe PDF	Download

Send Feedback

Authors

Lopes, Susana M. M.

Palacios, Francisco

Lemos, A.

Melo, Teresa M. V. D. Pinho e

Abstract(s)

A general route to 1,2-oxazines and open chain oximes bearing a 1H-tetrazolyl substituent via DielseAlder reaction of 3-(tetrazol-5-yl)-nitrosoalkenes is reported. It was also demonstrated that reduction of these adducts followed by deprotection of the tetrazolyl group give 5-(1-aminoalkyl)-1H-tetrazoles, a-amino acid analogues.

Keywords

Cicloadição Diels-Alder Heterocycles

URI

http://hdl.handle.net/10400.1/1046

Citation

Lopes, Susana M.M.; Palacios, Francisco; Lemos, A.; Melo, Teresa M.V.D.Pinho e. Diels–Alder reactions of 3-(1H-tetrazol-5-yl)-nitrosoalkenes: synthesis of functionalized 5-(substituted)-1H-tetrazoles. Tetrahedron, 67, 46, 8902-8909, 2011.