Repository logo
 
Publication

Myocardial deformation analysis using cardiac magnetic resonance in apical hypertrophic cardiomyopathy: is it an useful tool to predict adverse outcomes?

2023-07-08Journal article Restricted
Simple item page
dc.contributor.authorFernandes, Raquel
dc.contributor.authorBrandão, Mariana
dc.contributor.authorLopes, Ricardo Ladeiras
dc.contributor.authorFaria, Rita
dc.contributor.authorFerreira, Nuno Dias
dc.contributor.authorCarvalho, Ricardo Fontes
dc.date.accessioned2025-01-02T12:51:25Z
dc.date.available2025-01-02T12:51:25Z
dc.date.issued2023-07-08
dc.description.abstractApical hypertrophic cardiomyopathy (AHCM) has a broad phenotypic spectrum and still poses many diagnostic and prognostic challenges. Our team performed a retrospective study to examine the prognostic value of myocardial deformation obtained with cardiac magnetic resonance tissue tracking (CMR-TT) analysis in predicting adverse events in AHCM patients. We included patients with AHCM referred to CMR in our department from August 2009 to October 2021. CMR-TT analysis was performed to characterize the myocardial deformation pattern. Clinical, other complementary diagnostic exams characteristics and follow-up data were analysed. Primary endpoint was the composite of all-cause hospitalizations and mortality. During the 12-year period, 51 AHCM patients were evaluated by CMR, with a median age of 64 years-old and male predominance. 56,9% had an echocardiogram suggestive of AHCM. The most frequent phenotype was "the relative form" (43,1%). CMR evaluation revealed a median maximum left ventricle thickness of 15 mm and the presence of late gadolinium enhancement in 78,4%. Applying CMR-TT analysis, median global longitudinal strain was - 14,4%, with a median global radial strain of 30,4% and global circumferential strain of -18,0%. During a median follow-up of 5,3 years, the primary endpoint occurred in 21,3% of patients, with a hospitalization rate of 17,8% and all-cause mortality rate of 6,4%. After multivariable analysis, longitudinal strain rate in apical segments was an independent predictor of the primary endpoint (p = 0,023), showing that CMR-TT analysis could be useful in predicting adverse events in AHCM patients.eng
dc.identifier.doi10.1007/s10554-023-02902-1
dc.identifier.issn1875-8312
dc.identifier.urihttp://hdl.handle.net/10400.1/26560
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Science and Business Media
dc.relation.hasversionhttps://link.springer.com/article/10.1007/s10554-023-02902-1
dc.relation.ispartofThe International Journal of Cardiovascular Imaging
dc.rights.uriN/A
dc.subjectApical variant
dc.subjectCardiac magnetic resonance
dc.subjectHypertrophic cardiomyopathy
dc.subjectMyocardial strain
dc.subjectTissue tracking
dc.titleMyocardial deformation analysis using cardiac magnetic resonance in apical hypertrophic cardiomyopathy: is it an useful tool to predict adverse outcomes?eng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2003
oaire.citation.issue10
oaire.citation.startPage1997
oaire.citation.titleThe International Journal of Cardiovascular Imaging
oaire.citation.volume39
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameFernandes
person.givenNameRaquel
person.identifier.orcid0000-0002-2181-085X
relation.isAuthorOfPublicationfcd7ff9f-ab12-4280-9ea2-a62aba6ad351
relation.isAuthorOfPublication.latestForDiscoveryfcd7ff9f-ab12-4280-9ea2-a62aba6ad351

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Myocardial deformation analysis using cardiac magnetic resonance in apical hypertrophic cardiomyopathy.pdf
Size:
1.03 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.46 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ULS_10.1-MED-Artigos
ABC2-Artigos (em revistas ou actas indexadas)