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Antioxidant and anti-cholinesterase activities of Lavandula viridis L’Hér extracts after in vitro gastrointestinal digestion

dc.contributor.authorCosta, Patrícia
dc.contributor.authorGrevenstuk, Tomás
dc.contributor.authorCosta, Ana M. Rosa da
dc.contributor.authorGonçalves, Sandra
dc.contributor.authorRomano, Anabela
dc.date.accessioned2016-01-05T18:14:00Z
dc.date.available2016-01-05T18:14:00Z
dc.date.issued2014-04
dc.description.abstractLavandula viridis L’Hér is an aromatic shrub with relevant biological activities associated to the presence ofphenolic compounds. However, these compounds must be bioavailable to exert their biological function.Therefore, in this study, we investigated the influence of the L. viridis extract matrices on the digestion ofthe main component rosmarinic acid and their antioxidant and anti-cholinesterase activities after in vitrogastrointestinal digestion. Overall, the antioxidant and anti-cholinesterase activities were assured afterin vitro gastrointestinal processes and we observed that the L. viridis extract matrices have an importantrole in the bioactive effects of their main compound, rosmarinic acid. The L. viridis extracts and rosmarinicacid did not show any toxic effect on colon adenocarcinoma Caco-2 cell viability. Finally, the compoundsfrom L. viridis extracts were not metabolized by Caco-2 cells and were not able to permeate into them.pt_PT
dc.identifier.citationInd Crop Prod, 55 (2014) 83–89pt_PT
dc.identifier.doihttp://dx.doi.org/10.1016/j.indcrop.2014.01.049pt_PT
dc.identifier.issn0926-6690
dc.identifier.otherAUT: AMC01695; ARO01015;
dc.identifier.urihttp://hdl.handle.net/10400.1/7385
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationTHE ROLE OF AROMATIC PLANT COMPOUNDS IN THE PREVENTION AND TREATMENT OF NEUROLOGICAL DISORDERS
dc.relationPHYTOCHEMICAL PROFILES AND BIOLOGICAL ACTIVITY OF ENDEMIC PLANTS FROM THE MEDITERRANEAN REGION
dc.relationSTUDY OF STRESS TOLERANCE MECHANISMS IN METAL HYPERACCUMULATING PLANTS: HOW DO PLANTS COMPLEX AND TRANSPORT METALS
dc.subjectLavandula viridispt_PT
dc.subjectRosmarinic acidpt_PT
dc.subjectIn vitro digestionpt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectAnti-cholinesterase activitypt_PT
dc.titleAntioxidant and anti-cholinesterase activities of Lavandula viridis L’Hér extracts after in vitro gastrointestinal digestionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleTHE ROLE OF AROMATIC PLANT COMPOUNDS IN THE PREVENTION AND TREATMENT OF NEUROLOGICAL DISORDERS
oaire.awardTitlePHYTOCHEMICAL PROFILES AND BIOLOGICAL ACTIVITY OF ENDEMIC PLANTS FROM THE MEDITERRANEAN REGION
oaire.awardTitleSTUDY OF STRESS TOLERANCE MECHANISMS IN METAL HYPERACCUMULATING PLANTS: HOW DO PLANTS COMPLEX AND TRANSPORT METALS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F63505%2F2009/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/PIDDAC/SFRH%2FBPD%2F31534%2F2006/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F73293%2F2010/PT
oaire.citation.endPage89pt_PT
oaire.citation.startPage83pt_PT
oaire.citation.titleIndustrial Crops and Productspt_PT
oaire.citation.volume55pt_PT
oaire.fundingStreamPIDDAC
oaire.fundingStreamOE
person.familyNameGrevenstuk
person.familyNameRosa da Costa
person.familyNameGonçalves
person.familyNameRomano
person.givenNameTomás
person.givenNameAna M
person.givenNameSandra
person.givenNameAnabela
person.identifier305029
person.identifier.ciencia-idB31A-EC35-5A31
person.identifier.ciencia-idA418-A85E-5DB1
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0003-0779-3018
person.identifier.orcid0000-0003-0225-9537
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridE-2165-2012
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id24329026400
person.identifier.scopus-author-id53986075100
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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