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No β-N-Methylamino-L-alanine (BMAA) was detected in stranded cetaceans from Galicia (North-West Spain)

dc.contributor.authorSoliño, Lucia
dc.contributor.authorKim, Sea-Yong
dc.contributor.authorLópez, Alfredo
dc.contributor.authorCovelo, Pablo
dc.contributor.authorRydberg, Sara
dc.contributor.authorReis Costa, Pedro
dc.contributor.authorLage, Sandra
dc.date.accessioned2022-03-28T14:30:15Z
dc.date.available2022-03-28T14:30:15Z
dc.date.issued2022-02-23
dc.date.updated2022-03-24T14:47:07Z
dc.description.abstractThe neurotoxin β-N-methylamino-L-alanine (BMAA), a non-proteinogenic amino acid produced by several species of both prokaryotic (cyanobacteria) and eukaryotic (diatoms) microorganisms, has been proposed to be associated with the development of neurodegenerative diseases. At first, BMAA appeared to be ubiquitously present worldwide in various organisms, from aquatic and terrestrial food webs. However, recent studies, using detection methods based on mass spectrometry, instead of fluorescence detection, suggest that the trophic transfer of BMAA is debatable. This study evaluated BMAA in 22 cetaceans of three different species (<i>Phocoena phocoena</i>, <i>n</i> = 8, <i>Delphinus delphis</i>, <i>n</i> = 8, and <i>Tursiops truncatus</i>, <i>n</i> = 6), found stranded in North-West Spain. BMAA analysis of the liver, kidney, or muscle tissues via sensitive liquid chromatography with tandem mass spectrometry did not reveal the presence of this compound or its isomers. The absence recorded in this study highlights the need to better understand the trophic transfer of BMAA and its anatomical distribution in marine mammals.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifierdoi: 10.3390/jmse10030314
dc.identifier.citationJournal of Marine Science and Engineering 10 (3): 314 (2022)pt_PT
dc.identifier.doi10.3390/jmse10030314pt_PT
dc.identifier.issn2077-1312
dc.identifier.urihttp://hdl.handle.net/10400.1/17730
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationAlgarve Centre for Marine Sciences
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Environmental and Marine Studies
dc.relationEmergent toxins on the Portuguese coast: occurrence, transfer kinetics and toxicity
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMarine mammalspt_PT
dc.subjectPhycotoxinspt_PT
dc.subjectHarmful algae bloomspt_PT
dc.subjectBioaccumulationpt_PT
dc.subjectMarine food webspt_PT
dc.subjectAlzheimer diseasept_PT
dc.titleNo β-N-Methylamino-L-alanine (BMAA) was detected in stranded cetaceans from Galicia (North-West Spain)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleEmergent toxins on the Portuguese coast: occurrence, transfer kinetics and toxicity
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FCTA-AMB%2F30557%2F2017/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0094%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/101003376/EU
oaire.citation.issue3pt_PT
oaire.citation.startPage314pt_PT
oaire.citation.titleJournal of Marine Science and Engineeringpt_PT
oaire.citation.volume10pt_PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamH2020
person.familyNameSoliño
person.familyNameReis Costa
person.familyNameLage
person.givenNameLucia
person.givenNamePedro
person.givenNameSandra
person.identifier600820
person.identifier454970
person.identifier.ciencia-id2F12-68AC-8F6C
person.identifier.ciencia-idC911-9715-E547
person.identifier.ciencia-idDA15-C119-BDC8
person.identifier.orcid0000-0001-8356-5688
person.identifier.orcid0000-0001-6083-470X
person.identifier.orcid0000-0003-0167-7163
person.identifier.ridN-1908-2019
person.identifier.scopus-author-id7201895802
person.identifier.scopus-author-id54585529500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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