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Contamination and carcinogenic risks of lead in lip cosmetics in China

dc.contributor.authorGong, Yu
dc.contributor.authorChu, Junru
dc.contributor.authorKwong, Raymond
dc.contributor.authorNunes, Luís
dc.contributor.authorZhao, Di
dc.contributor.authorTang, Wenli
dc.contributor.authorLi, Chengjiu
dc.contributor.authorWei, Zhongbo
dc.contributor.authorJu, Yongming
dc.contributor.authorLi, Hongbo
dc.contributor.authorMa, Lena Q.
dc.contributor.authorYu, Xiezhi
dc.contributor.authorZhong, Huan
dc.date.accessioned2024-02-19T10:42:00Z
dc.date.available2024-02-19T10:42:00Z
dc.date.issued2024
dc.description.abstractThere are growing concerns about elevated lead (Pb) levels in lip cosmetics, yet in China, the largest lip cosmetic market, recent Pb contamination in lip cosmetics and associated Pb exposure remain unclear. Here, we measured Pb levels of 29 popular lip cosmetics in China and conducted the bioaccessibility-corrected carcinogenic risk assessments and sensitivity analysis regarding Pb exposure for consumers using Monte Carlo simulation. The Pb concentrations of collected samples ranged from undetectable (< 0.05 mu g/kg) to 0.21 mg/kg, all of which were well below the Pb concentration limit set for cosmetics in China (10 mg/kg). The 50th percentile incremental lifetime cancer risk (ILCR) of Pb in Chinese cosmetics (1.20E-07) was below the acceptable level (1E-06), indicating that the application of lip cosmetics and subsequent Pb exposure does not pose carcinogenic risks to consumers in most cases. The results of this study provide new insights into understanding the Pb risk in lip cosmetics.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1007/s00128-024-03851-8pt_PT
dc.identifier.issn0007-4861
dc.identifier.urihttp://hdl.handle.net/10400.1/20410
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.subjectLeadpt_PT
dc.subjectLip cosmeticspt_PT
dc.subjectHealth risk assessmentpt_PT
dc.subjectCarcinogenic riskpt_PT
dc.titleContamination and carcinogenic risks of lead in lip cosmetics in Chinapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.titleBulletin of Environmental Contamination and Toxicologypt_PT
oaire.citation.volume112pt_PT
person.familyNameNunes
person.givenNameLuís
person.identifier93800
person.identifier.ciencia-id3112-1FCD-6685
person.identifier.orcid0000-0001-5606-970X
person.identifier.ridM-4647-2013
person.identifier.scopus-author-id7102529511
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd32d0ac6-6cb6-4f03-afcf-3c80978d469f
relation.isAuthorOfPublication.latestForDiscoveryd32d0ac6-6cb6-4f03-afcf-3c80978d469f

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