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Thermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream

2017-06Journal article Open access
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dc.contributor.authorMateus, Ana
dc.contributor.authorA Costa, Rita
dc.contributor.authorCardoso, João CR
dc.contributor.authorAndree, Karl B.
dc.contributor.authorEstevez, Alicia
dc.contributor.authorGisbert, Enric
dc.contributor.authorPower, Deborah
dc.date.accessioned2019-11-20T15:07:34Z
dc.date.available2019-11-20T15:07:34Z
dc.date.issued2017-06
dc.description.abstractThe impact of thermal imprinting on the plasticity of the hypothalamic-pituitary-interrenal (HPI) axis and stress response in an adult ectotherm, the gilthead sea bream (Sparus aurata, L.), during its development was assessed. Fish were reared under 4 thermal regimes, and the resulting adults exposed to acute confinement stress and plasma cortisol levels and genes of the HPI axis were monitored. Changes in immune function, a common result of stress, were also evaluated using histomorphometric measurements of melanomacrophages centers (MMCs) in the head kidney and by monitoring macrophage-related transcripts. Thermal history significantly modified the HPI responsiveness in adult sea bream when eggs and larvae were reared at a higher than optimal temperature (HT, 22 degrees C), and they had a reduced amplitude in their cortisol response and significantly upregulated pituitary pomc and head kidney star transcripts. Additionally, after an acute stress challenge, immune function was modified and the head kidney of adult fish reared during development at high temperatures (HT and LHT, 18-22 degrees C) had a decreased number of MMCs and a significant downregulation of dopachrome tautomerase. Thermal imprinting during development influenced adult sea bream physiology and increased plasma levels of glucose and sodium even in the absence of an acute stress in fish reared under a high-low thermal regime (HLT, 22-18 degrees C). Overall, the results demonstrate that temperature during early development influences the adult HPI axis and immune function in a teleost fish.
dc.description.sponsorshipproject Lifecycle EU-FP7 [222719]
dc.description.sponsorshipFCT- Foundation for Science and Technology [CCMAR/Multi/04326/2013]
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1530/JOE-16-0610
dc.identifier.issn0022-0795
dc.identifier.issn1479-6805
dc.identifier.urihttp://hdl.handle.net/10400.1/13106
dc.language.isoeng
dc.peerreviewedyes
dc.publisherBioScientifica
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectSparus-aurata L.
dc.subjectAcute regulatory protein
dc.subjectGilthead seabream
dc.subjectRainbow-trout
dc.subjectMelanomacrophage centers
dc.subjectDicentrarchus-labrax
dc.subjectCortisol response
dc.subjectDna methylation
dc.subjectImage-analysis
dc.subjectHead kidney
dc.titleThermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F81625%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04326%2F2013/PT
oaire.citation.endPage394
oaire.citation.issue3
oaire.citation.startPage381
oaire.citation.titleJournal of Endocrinology
oaire.citation.volume233
oaire.fundingStreamSFRH
oaire.fundingStream5876
person.familyNameMateus
person.familyNameCosta
person.familyNameCardoso
person.familyNameGisbert
person.familyNamePower
person.givenNameAna Patrícia
person.givenNameRita
person.givenNameJoão
person.givenNameEnric
person.givenNameDeborah Mary
person.identifier14332
person.identifier606918
person.identifier.ciencia-id2816-E389-626E
person.identifier.ciencia-id8219-DFF3-929F
person.identifier.ciencia-id8B16-F203-2AFC
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.orcid0000-0003-2045-1047
person.identifier.orcid0000-0002-6975-7576
person.identifier.orcid0000-0001-7890-0170
person.identifier.orcid0000-0002-7457-8468
person.identifier.orcid0000-0003-1366-0246
person.identifier.ridO-9136-2018
person.identifier.ridM-4151-2013
person.identifier.ridB-3654-2011
person.identifier.scopus-author-id57097731700
person.identifier.scopus-author-id7201822956
person.identifier.scopus-author-id7101806760
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
rcaap.typearticle
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