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Molecular basis of spermatogenesis and sperm quality

2017-05Journal article Restricted access
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dc.contributor.authorRobles, Vanesa
dc.contributor.authorHerraez, Paz
dc.contributor.authorLabbe, Catherine
dc.contributor.authorCabrita, Elsa
dc.contributor.authorPsenicka, Martin
dc.contributor.authorValcarce, David G.
dc.contributor.authorF RIESCO, MARTA
dc.date.accessioned2019-11-20T15:07:39Z
dc.date.available2019-11-20T15:07:39Z
dc.date.issued2017-05
dc.description.abstractSpermatozoan quality can be evaluated in different ways, here we focus on the analysis of DNA, RNA and epigenetic status of germ cells. These characterizations also can be the bases for explaining sperm quality at other levels, so we will see how some of these molecules could affect other sperm quality markers. Moreover, we consider the possibility of using some of these molecules as predictors of sperm quality in terms of the ability to produce healthy offspring. The relevant effect of different types of RNA molecules in germ line specification and spermatogenesis and the importance of germ cell DNA integrity and a proper epigenetic pattern will be also discussed. Although most studies at this level have been performed in mammals, some information is available for fish; these recent discoveries in fish models are included. We provide a general overview on how these molecules could have a deep influence in the final sperm quality.(C) 2016 Elsevier Inc. All rights reserved.
dc.description.sponsorshipMINECO [AGL2015-68330-C2-1-R]
dc.description.sponsorshipCOST Office (Food and Agriculture COST Action FA1205: AQUAGAMETE)
dc.description.sponsorshipFundacion Ramon Areces
dc.description.sponsorshipMinisterio de Ciencia e Innovacion MICINN [MICINN AGL2009-06994, AGL2014-53167-C3-3-R]
dc.description.sponsorshipRamon y Cajal Program [RYC-2008-02339]
dc.description.sponsorshipJunta de Castilla y Leon [E-24-2009-0036681 EDU/1084/2012]
dc.description.sponsorshipFondo Social Europeo
dc.description.sponsorshipMinistry of Education, Youth and Sports of the Czech Republic [CZ.1.05/2.1.00/01.0024, L01205]
dc.description.sponsorshipCzech Science Foundation [P502/13/26952S]
dc.description.sponsorshipFrench CRB Anim project Investissements d'avenir [ANR11-INBS-0003]
dc.description.sponsorship[CRIOBIV-31-03-05-FEP-59]
dc.description.sponsorship[REPLING 31-03-05FEP-69]
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1016/j.ygcen.2016.04.026
dc.identifier.issn0016-6480
dc.identifier.issn1095-6840
dc.identifier.urihttp://hdl.handle.net/10400.1/13151
dc.language.isoeng
dc.peerreviewedyes
dc.publisherAcademic Press Inc Elsevier Science
dc.subjectMale germ-cells
dc.subjectEarly embryo development
dc.subjectBisphenol-A exposure
dc.subjectChromatoid body
dc.subjectMessenger-rna
dc.subjectDna-damage
dc.subjectZebrafish
dc.subjectMicrornas
dc.subjectSpermatozoa
dc.subjectExpression
dc.titleMolecular basis of spermatogenesis and sperm quality
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage9
oaire.citation.startPage5
oaire.citation.titleGeneral and Comparative Endocrinology
oaire.citation.volume245
person.familyNameCabrita
person.familyNameF RIESCO
person.givenNameElsa
person.givenNameMARTA
person.identifier.orcid0000-0003-3864-8841
person.identifier.orcid0000-0002-3655-6401
person.identifier.ridE-8523-2012
person.identifier.ridO-9766-2014
person.identifier.scopus-author-id26645697000
person.identifier.scopus-author-id54796976600
rcaap.rightsrestrictedAccess
rcaap.typearticle
relation.isAuthorOfPublication332fa9b9-09b5-47fe-a1b3-afe088b4150a
relation.isAuthorOfPublication9e0d4fdf-78d3-4eda-85a2-ff13b385449b
relation.isAuthorOfPublication.latestForDiscovery9e0d4fdf-78d3-4eda-85a2-ff13b385449b

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