The davydov/scott model for energy storage and transport in proteins

Cruzeiro, Leonor

http://hdl.handle.net/10400.1/3544

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
3544 handle - The Davydov_Scott model.pdf		623.82 KB	Adobe PDF	Download

Send Feedback

Authors

Cruzeiro, Leonor

Abstract(s)

The current status of the Davydov/Scott model for energy transfer in proteins is reviewed. After a brief introduction to the theoretical framework and to the basic results, the problems of finite temperature dynamics and of the full quantum and mixed quantum-classical approximations are described, as well as recent results obtained within each of these approximations. A short survey of experimental evidence in support of the Davydov/Scott model is made and absorption spectra are calculated that show the same temperature dependence as that measured in crystalline acetanilide. Future applications of the Davydov/Scott model to protein folding and function and to misfolding diseases are outlined