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Proteome dataset of sea bass (Dicentrarchus labrax) skin-scales exposed to fluoxetine and estradiol

2022-04Journal article Open access
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dc.contributor.authorL, Anjos
dc.contributor.authorPI Pinto, PPinto
dc.contributor.authorSantos, Soraia
dc.contributor.authorEstêvão, M. Dulce
dc.contributor.authorSanta, Cátia
dc.contributor.authorManadas, Bruno
dc.contributor.authorCanario, A.V.M.
dc.contributor.authorPower, Deborah
dc.date.accessioned2022-09-19T13:23:44Z
dc.date.available2022-09-19T13:23:44Z
dc.date.issued2022-04
dc.description.abstractContamination of aquatic ecosystems with anthropogenic pollutants, including pharmaceutical drugs, is a major concern worldwide. Aquatic organisms such as fish are particularly at risk of exposure to pollutants. The surface of fish is the first point of contact with pollutants, but few studies have considered the impact of pollutants on the skin-scale barrier. The present proteome data are the basis of the findings discussed in the associated research article "Proteomics of sea bass skin-scales exposed to the emerging pollutant fluoxetine compared to estradiol" [1]. Juvenile sea bass were exposed by intraperitoneal injections to: a) the antidepressant fluoxetine (FLX), a widely prescribed psychotropic drug and an emerging pollutant; b) the natural estrogen 17 beta-estradiol (E2) and c) the vehicle, coconut oil (control). The scale proteome of fish exposed to these compounds for 5 days was analysed using quantitative label-free proteomics technology SWATH-MS (sequential windowed data-independent a cquisition of the total high-resolution-mass spectra). The proteome data generated was submitted to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD020983. LC-MS data from pooled protein extracts from the scales of all experimental groups was acquired using information-dependent acquisition (IDA) and 1,254 proteins were identified by searching against the sea bass genome database. 715 proteins were quantified by SWATH acquisition, and 213 proteins had modified levels (p < 0.05) between the E2- or FLX-exposed fish compared to the control. The main biological processes and KEGG pathways affected by E2 or FLX treatments were identified using Cytoscape/ClueGO enrichment analyses. (c) 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)pt_PT
dc.description.sponsorshipPOCI-01-0145-FEDER-402-022125; MAR-01.03.01-FEAMP-0050; EMBRC.PT ALG-01-0145-FEDER-022121, ROTEIRO/0028/2013; POCI-01-0145-FEDER-016428
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.dib.2022.107971pt_PT
dc.identifier.issn2352-3409
dc.identifier.urihttp://hdl.handle.net/10400.1/18264
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationE2SCALE: Scaling-down estrogenic responses in fish
dc.relationAlgarve Centre for Marine Sciences
dc.relationEuropean Marine Biological Research Infrastructure Cluster to promote the Blue Bioeconomy
dc.relationOptImization of novel value CHains for fish and seafood by developing an integraTed sustainable approacH for improved qualitY, safety and waSte reduction
dc.relationNot Available
dc.relationCenter for Innovative Biomedicine and Biotechnology
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSWATH-MS quantitative proteomicspt_PT
dc.subjectScalespt_PT
dc.subjectEmerging pollutantspt_PT
dc.subjectAntidepressantpt_PT
dc.subjectEstrogenpt_PT
dc.titleProteome dataset of sea bass (Dicentrarchus labrax) skin-scales exposed to fluoxetine and estradiolpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleE2SCALE: Scaling-down estrogenic responses in fish
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleEuropean Marine Biological Research Infrastructure Cluster to promote the Blue Bioeconomy
oaire.awardTitleOptImization of novel value CHains for fish and seafood by developing an integraTed sustainable approacH for improved qualitY, safety and waSte reduction
oaire.awardTitleNot Available
oaire.awardTitleCenter for Innovative Biomedicine and Biotechnology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FAAG-GLO%2F4003%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/654008/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/872217/EU
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/DL 57%2F2016/DL 57%2F2016%2FCP1361%2FCT0001/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04539%2F2020/PT
oaire.citation.startPage107971pt_PT
oaire.citation.titleData in Briefpt_PT
oaire.citation.volume41pt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamH2020
oaire.fundingStreamH2020
oaire.fundingStreamDL 57/2016
oaire.fundingStream6817 - DCRRNI ID
person.familyNameAnjos Guerreiro
person.familyNamePinto
person.familyNameSantos
person.familyNameEstêvão
person.familyNameCanario
person.familyNamePower
person.givenNameLiliana Isabel Tomé
person.givenNamePatricia IS
person.givenNameSoraia
person.givenNameMaria Dulce da Mota Antunes de Oliveira
person.givenNameAdelino
person.givenNameDeborah Mary
person.identifierAAK-3800-2020
person.identifier643457
person.identifierI-4695-2014
person.identifier143624
person.identifier.ciencia-id6D18-2D1C-A45C
person.identifier.ciencia-idE51D-5CCB-B1C6
person.identifier.ciencia-idEF18-F0AF-D388
person.identifier.ciencia-id881B-53E8-0DB1
person.identifier.ciencia-id1F1E-D3B3-F804
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.orcid0000-0001-9474-522X
person.identifier.orcid0000-0001-7854-3898
person.identifier.orcid0000-0001-5006-2021
person.identifier.orcid0000-0002-7151-8363
person.identifier.orcid0000-0002-6244-6468
person.identifier.orcid0000-0003-1366-0246
person.identifier.ridM-3817-2013
person.identifier.ridC-1328-2018
person.identifier.ridC-7942-2009
person.identifier.scopus-author-id8575757700
person.identifier.scopus-author-id10240774300
person.identifier.scopus-author-id8381590400
person.identifier.scopus-author-id56568523700
person.identifier.scopus-author-id7101806760
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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