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Phylogeny and evolution of medical species of candida and related taxa: a multigenic analysis

dc.contributor.authorDiezmann, S.
dc.contributor.authorCox, C. J.
dc.contributor.authorSchönian, G.
dc.contributor.authorVilgalys, R.
dc.contributor.authorMitchell, T. G.
dc.date.accessioned2014-10-27T15:34:31Z
dc.date.available2014-10-27T15:34:31Z
dc.date.issued2004
dc.date.updated2014-10-24T10:06:12Z
dc.description.abstractHemiascomycetes are species of yeasts within the order Saccharomycetales. The order encompasses disparate genera with a variety of life styles, including opportunistic human pathogens (e.g., Candida albicans), plant pathogens (e.g., Eremothecium gossypii), and cosmopolitan yeasts associated with water and decaying vegetation. To analyze the phylogeny of medically important species of yeasts, we selected 38 human pathogenic and related strains in the order Saccharomycetales. The DNA sequences of six nuclear genes were analyzed by maximum likelihood and Bayesian phylogenetic methods. The maximum likelihood analysis of the combined data for all six genes resolved three major lineages with significant support according to Bayesian posterior probability. One clade was mostly comprised of pathogenic species of Candida. Another major group contained members of the family Metschnikowiaceae as a monophyletic group, three species of Debaryomyces, and strains of Candida guilliermondii. The third clade consisted exclusively of species of the family Saccharomycetaceae. Analysis of the evolution of key characters indicated that both codon reassignment and coenzyme Q9 likely had single origins with multiple losses. Tests of correlated character evolution revealed that these two traits evolved independently.por
dc.identifier.citationDiezmann, S.; Cox, C.J.; Schönian, G.; Vilgalys, R.J.; Mitchell, T.G. Phylogeny and evolution of medical species of candida and related taxa: A multigenic analysis, Journal of Clinical Microbiology, 42, 12, 5624-56, 2004.por
dc.identifier.doihttp://dx.doi.org/10.1128/JCM.42.12.5624–5635.2004
dc.identifier.issn0095-1137
dc.identifier.urihttp://hdl.handle.net/10400.1/5535
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAmerican Society for Microbiologypor
dc.relation.publisherversion12por
dc.titlePhylogeny and evolution of medical species of candida and related taxa: a multigenic analysispor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage56por
oaire.citation.startPage5624por
oaire.citation.titleJournal of Clinical Microbiologypor
oaire.citation.volume42por
person.familyNameCox
person.givenNameCymon
person.identifier.ciencia-id6B15-9771-1D04
person.identifier.orcid0000-0002-4927-979X
person.identifier.ridD-1303-2012
person.identifier.scopus-author-id7402112716
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication82c3689c-60b6-440d-9d7b-49e6dbd6861b
relation.isAuthorOfPublication.latestForDiscovery82c3689c-60b6-440d-9d7b-49e6dbd6861b

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