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Anti-oxidant, Anti-inflammatory and Anti-proliferative Activities of Moroccan Commercial Essential Oils

dc.contributor.authorS, Azza
dc.contributor.authorLyoussi, B.
dc.contributor.authorMegias, C.
dc.contributor.authorCortes Giraldo, I.
dc.contributor.authorVioque, J.
dc.contributor.authorFigueiredo, A. C.
dc.contributor.authorMiguel, Maria Graça
dc.date.accessioned2015-06-15T14:53:34Z
dc.date.available2015-06-15T14:53:34Z
dc.date.issued2014
dc.description.abstractEssential oils (EO) possess antimicrobial, anti-inflammatory, insect repellent, anti-cancer, and antioxidant properties, among others. In the present work, the antioxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial EOs (Citrus aurantium, C. union, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare and Thymus vulgaris) were evaluated and compared with their main constituents. T. vulgaris EO showed the best free radicals scavenging capacity. This EO was also the most effective against lipid peroxidation along with C. limon and F. vulgare EOs. C. sempervirens EO was the most effective in scavenging NO free radicals, whereas C. limon EO showed the best chelating power. Not all of the major compounds of the EO were responsible for the whole activity of the EOs. T. vulgaris EO showed the best anti-proliferative activity against THP-1 cells in contrast to that of F. vulgare. The antioxidant and anti-inflammatory activities of the EOs were plant species dependent and not always attributable to the EOs main components. Nevertheless, the EOs anti-proliferative activities were more related to their main components, as with T. vulgaris, C. limon, E. globulus and C. sempervirens.
dc.identifier.issn1934-578X
dc.identifier.issn1555-9475
dc.identifier.otherAUT: MGM00322;
dc.identifier.urihttp://hdl.handle.net/10400.1/6340
dc.language.isoeng
dc.peerreviewedyes
dc.publisherNatural Products
dc.relation.isbasedonP-009-A6K
dc.titleAnti-oxidant, Anti-inflammatory and Anti-proliferative Activities of Moroccan Commercial Essential Oils
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage594
oaire.citation.startPage587
oaire.citation.titleNatural Product Communications
oaire.citation.volume9
person.familyNameAAZZA
person.familyNameMiguel
person.givenNameSmail
person.givenNameMaria da Graça
person.identifier1426445
person.identifier.ciencia-idE416-77DF-6A97
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.orcid0000-0002-9339-8999
person.identifier.orcid0000-0003-2507-4228
person.identifier.ridL-7630-2017
person.identifier.scopus-author-id51664684500
person.identifier.scopus-author-id35562054500
rcaap.rightsrestrictedAccess
rcaap.typearticle
relation.isAuthorOfPublicationa4c35de9-6854-4197-b8dc-541c90827314
relation.isAuthorOfPublication2507350f-9e60-4d4a-a096-53e58d93549c
relation.isAuthorOfPublication.latestForDiscoverya4c35de9-6854-4197-b8dc-541c90827314

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