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Evaluation of the antioxidant and antimicrobial properties of in vitro cultured Drosera intermedia extracts

2009Journal article Restricted access
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dc.contributor.authorGrevenstuk, Tomás
dc.contributor.authorGonçalves, Sandra
dc.contributor.authorAlmeida, Sara
dc.contributor.authorCoelho, Natacha
dc.contributor.authorQuintas, Célia
dc.contributor.authorGaspar, Maria Nelma
dc.contributor.authorRomano, Anabela
dc.date.accessioned2013-03-13T13:17:41Z
dc.date.available2013-03-13T13:17:41Z
dc.date.issued2009
dc.description.abstractEvaluation of the antioxidant activity of the methanol, water and n-hexane extracts of Drosera intermedia, determined by the Folin-Ciocalteau (F-C), trolox equivalent antioxidant capacity (TEAC) and oxygen radical antioxidant capacity (ORAC) assays showed that the methanol extract had the highest antioxidant activity (F-C: 378.6 ± 31.5 μmolGAE/mgextract; TEAC: 332.2 ± 29.1 μmolTE/mgextract; ORAC: 64.7 ± 7.8 μmolTE/mgextract). Antimicrobial activity was tested against seven bacterial and eight yeast strains using the agar diffusion assay, followed by the determination of minimum inhibitory concentrations (MIC). All tested D. intermedia extracts demonstrated strong antimicrobial properties with a broad spectrum of activity. However, the n-hexane extract exhibited much greater activity than water and methanol extracts. The most susceptible microorganisms to the n-hexane extract were Staphylococcus epidermidis ATCC 12228 and Candida albicans YP0175, for which a MIC value of 13.0 μg/mL was scored.por
dc.description.sponsorshipTomás Grevenstuk and Sandra Gonçalves acknowledge a grant from the Portuguese Science and Technology Foundation (FCT, Grant SFRH/BD/31777/2006 and SFRH/BPD/31534/2006, respectively).por
dc.identifier.citationGrevenstuk T., Gonçalves S., Almeida S., Coelho N., Quintas C., Romano A. 2009. Evaluation of antioxidant and antimicrobial properties of in vitro cultured Drosera intermedia, Natural Product Communications 4: 1063-1068por
dc.identifier.issn1934-578X
dc.identifier.otherAUT: ARO01015;CQU00490;
dc.identifier.urihttp://hdl.handle.net/10400.1/2566
dc.language.isoengpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.naturalproduct.us/JournalArchive.asppor
dc.subjectIn vitro culturepor
dc.subjectF-Cpor
dc.subjectTEACpor
dc.subjectORACpor
dc.subjectAgar diffusion assaypor
dc.subjectMICpor
dc.titleEvaluation of the antioxidant and antimicrobial properties of in vitro cultured Drosera intermedia extractspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1068por
oaire.citation.issue8por
oaire.citation.startPage1063por
oaire.citation.titleNatural Product Communicationspor
oaire.citation.volume4por
person.familyNameGrevenstuk
person.familyNameGonçalves
person.familyNameCoelho
person.familyNameQuintas
person.familyNameRomano
person.givenNameTomás
person.givenNameSandra
person.givenNameNatacha
person.givenNameCélia
person.givenNameAnabela
person.identifier.ciencia-idB31A-EC35-5A31
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-idC518-BDB3-E127
person.identifier.ciencia-idEA14-D76B-FF6E
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0003-0779-3018
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0003-4265-5622
person.identifier.orcid0000-0001-9680-5089
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id24329026400
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication4ae6491f-f21f-4001-8987-dec1ad73ca5c
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