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Two toll-like receptors identified in the mantle of Mytilus coruscus are abundant in haemocytes

dc.contributor.authorLi, Yi-Feng
dc.contributor.authorLiu, Yu-Zhu
dc.contributor.authorChen, Yan-Wen
dc.contributor.authorChen, Ke
dc.contributor.authorBatista, Frederico
dc.contributor.authorCardoso, João CR
dc.contributor.authorChen, Yu-Ru
dc.contributor.authorPeng, Li-Hua
dc.contributor.authorZhang, Ya
dc.contributor.authorZhu, You-Ting
dc.contributor.authorLiang, Xiao
dc.contributor.authorPower, Deborah
dc.contributor.authorYang, Jin-Long
dc.date.accessioned2020-07-24T10:52:05Z
dc.date.available2020-07-24T10:52:05Z
dc.date.issued2019-07
dc.description.abstractToll-like receptors (TLRs) are a large family of pattern recognition receptors (PREs) that play a critical role in innate immunity. TLRs are activated when they recognize microbial associated molecular patterns (MAMPs) of bacteria, viruses, or fungus. In the present study, two TLRs were isolated from the mantle of the hard-shelled mussel (Mytilus coruscus) and designated McTLR2 and McTLR3 based on their sequence similarity and phylogenetic clustering with Crassostrea gigas, CgiTLR2 and CgiTLR3, respectively. Quantitative RT-PCR analysis demonstrated that McTLR2 and McTLR3 were constitutively expressed in many tissues but at low abundance.
dc.description.sponsorshipMinistry of Science and Technology of ChinaMinistry of Science and Technology, China [2016YFE0131900]
dc.description.sponsorshipNational Natural Science Foundation of ChinaNational Natural Science Foundation of China [41476131]
dc.description.sponsorshipPeak Discipline Program for Fisheries from the Shanghai Municipal Government
dc.description.sponsorshipFundacao para a Ciencia e a Tecnologia, PortugalPortuguese Foundation for Science and Technology [UID/Multi/04326/2013]
dc.description.sponsorshipFCT/China bilateral cooperation project [441]
dc.identifier.doi10.1016/j.fsi.2019.05.001
dc.identifier.issn1050-4648
dc.identifier.issn1095-9947
dc.identifier.urihttp://hdl.handle.net/10400.1/14312
dc.language.isoeng
dc.peerreviewedyes
dc.publisherAcademic Press Ltd- Elsevier Science
dc.subjectActivate B-cells
dc.subjectComplete Cds
dc.subjectExpression
dc.subjectMyd88
dc.titleTwo toll-like receptors identified in the mantle of Mytilus coruscus are abundant in haemocytes
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04326%2F2013/PT
oaire.citation.endPage140
oaire.citation.startPage134
oaire.citation.titleFish and Shellfish Immunology
oaire.citation.volume90
oaire.fundingStream5876
person.familyNameBatista
person.familyNameCardoso
person.familyNamePower
person.givenNameFrederico
person.givenNameJoão
person.givenNameDeborah Mary
person.identifier14332
person.identifier.ciencia-idCB1B-7DBC-6303
person.identifier.ciencia-id8B16-F203-2AFC
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.orcid0000-0002-2848-3011
person.identifier.orcid0000-0001-7890-0170
person.identifier.orcid0000-0003-1366-0246
person.identifier.ridF-5651-2010
person.identifier.ridM-4151-2013
person.identifier.scopus-author-id7003808684
person.identifier.scopus-author-id7201822956
person.identifier.scopus-author-id7101806760
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccess
rcaap.typearticle
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