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Microbial communities and bioactive compounds in marine sponges of the family Irciniidae-a review

2014-10Journal article Open access
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dc.contributor.authorHardoim, Cristiane C. P.
dc.contributor.authorCosta, Rodrigo
dc.date.accessioned2018-12-07T14:58:04Z
dc.date.available2018-12-07T14:58:04Z
dc.date.issued2014-10
dc.description.abstractMarine sponges harbour complex microbial communities of ecological and biotechnological importance. Here, we propose the application of the widespread sponge family Irciniidae as an appropriate model in microbiology and biochemistry research. Half a gram of one Irciniidae specimen hosts hundreds of bacterial species-the vast majority of which are difficult to cultivate-and dozens of fungal and archaeal species. The structure of these symbiont assemblages is shaped by the sponge host and is highly stable over space and time. Two types of quorum-sensing molecules have been detected in these animals, hinting at microbe-microbe and host-microbe signalling being important processes governing the dynamics of the Irciniidae holobiont. Irciniids are vulnerable to disease outbreaks, and concerns have emerged about their conservation in a changing climate. They are nevertheless amenable to mariculture and laboratory maintenance, being attractive targets for metabolite harvesting and experimental biology endeavours. Several bioactive terpenoids and polyketides have been retrieved from Irciniidae sponges, but the actual producer (host or symbiont) of these compounds has rarely been clarified. To tackle this, and further pertinent questions concerning the functioning, resilience and physiology of these organisms, truly multi-layered approaches integrating cutting-edge microbiology, biochemistry, genetics and zoology research are needed.
dc.description.sponsorshipPortuguese Foundation [PTDC/MAR/101431/2008, PTDC/BIA-MIC/3865/2012]; European Regional Development Fund (ERDF) through the Operational Competitiveness Programme (COMPETE); national funds through FCT (Foundation for Science and Technology) [PEst-C/MAR/LA0015/2011]; FCT [SFRH/BD/60873/2009]
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.3390/md12105089
dc.identifier.issn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.1/11839
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI Ag
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectBarrier-reef sponge
dc.subjectQuorum sensing inhibitors
dc.subjectBryozoan Bugula-Neritina
dc.subjectCell genomics reveals
dc.subjectVertical transmission
dc.subjectBacterial communities
dc.subjectAntimicrobial activities
dc.subjectRhopaloeides-odorabile
dc.subjectMediterranean sea
dc.subjectCyanobacterial symbionts
dc.titleMicrobial communities and bioactive compounds in marine sponges of the family Irciniidae-a review
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FMAR%2F101431%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBIA-MIC%2F3865%2F2012/PT
oaire.citation.endPage5122
oaire.citation.issue10
oaire.citation.startPage5089
oaire.citation.titleMarine Drugs
oaire.citation.volume12
oaire.fundingStream3599-PPCDT
oaire.fundingStream3599-PPCDT
person.familyNameHardoim
person.familyNameda Silva Costa
person.givenNameCristiane
person.givenNameRodrigo
person.identifier115920
person.identifier.ciencia-id5917-D500-D251
person.identifier.orcid0000-0003-4650-0177
person.identifier.orcid0000-0002-5932-4101
person.identifier.ridD-4544-2015
person.identifier.ridN-7274-2013
person.identifier.scopus-author-id7203063627
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
rcaap.typearticle
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