Repository logo
 
Publication

Treatment patterns and preferences of people living with HIV starting or switching antiretroviral therapy: real-world evidence from Portugal

2024-07-25Journal article Open access
Simple item page
dc.contributor.authorPedro, Liliana
dc.contributor.authorZagalo, Alexandra
dc.contributor.authorTavares, Raquel
dc.contributor.authorPacheco, Patrícia
dc.contributor.authorOliveira, Joaquim
dc.contributor.authorPinto, Inês Vaz
dc.contributor.authorSerrão, Rosário
dc.contributor.authorTavares, Sandra
dc.contributor.authorBrito, Paula
dc.contributor.authorMaltez, Fernando
dc.contributor.authorNeves, Isabel
dc.contributor.authorCarvalho, Alexandre
dc.contributor.authorTeófilo, Eugénio
dc.contributor.authorAlmeida, Joana
dc.contributor.authorLains, Inês
dc.date.accessioned2024-12-30T12:44:13Z
dc.date.available2024-12-30T12:44:13Z
dc.date.issued2024-07-25
dc.description.abstractBackground: There is a lack of up-to-date real-life evidence on antiretroviral therapy (ART) strategies among people living with HIV (PLWH) in Portugal. This study aimed to describe the treatment strategy used in PLWH either initiating or switching ART. Methods: Non-interventional, cross-sectional, multicenter study carried out between December 2019 and October 2021 in Portugal. Results: A total of 237 PLWH were included in this study, 171 of whom were ART-experienced and 66 were ART-na¨ıve. The study showed that triple regimens were the most common ART strategy and integrase strand transfer inhibitors-based therapy was the most frequently used therapeutic class in both ART-na¨ıve and ART-experienced PLWH. Nevertheless, about a third of PLWH who started a triple regimen transitioned to a dual regimen. Patient-reported outcomes revealed high HIV literacy and similar ART preferences in both groups. Conclusions: This real-world study showed that triple regimens were the most widely used ART strategy, even after the European AIDS Clinical Society guidelines introduced the recommendation of a dual regimen for na¨ıve patients. The cohorts of this study presented a high level of HIV literacy at the time of inclusion. Our findings highlighted that taking pills only once a day is considered a very important feature for most patients.eng
dc.identifier.doi10.1177/09564624241263122
dc.identifier.issn0956-4624
dc.identifier.issn1758-1052
dc.identifier.urihttp://hdl.handle.net/10400.1/26549
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSAGE Publications
dc.relation.hasversionhttps://journals.sagepub.com/doi/10.1177/09564624241263122?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
dc.relation.ispartofInternational Journal of STD & AIDS
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAntiretroviral therapy
dc.subjectHIV
dc.subjectAntiretroviral therapy-experienced patient
dc.subjectAntiretroviral therapy-naïve patient
dc.subjectQuality of life
dc.titleTreatment patterns and preferences of people living with HIV starting or switching antiretroviral therapy: real-world evidence from Portugaleng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage883
oaire.citation.issue11
oaire.citation.startPage873
oaire.citation.titleInternational Journal of STD & AIDS
oaire.citation.volume35
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Treatment-patterns-and-preferences-of-people-living-with-hiv-starting-or-switching-antiretroviral.pdf
Size:
685.69 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.46 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ULS_10.1-MED-Artigos