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Evaluation of antioxidant and anthelmintic properties of tithonia diversifolia extracts against gastrointestinal nematode eggs using in vitro assays

2025-08-01Journal article Restricted access
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dc.contributor.authorMeza Ocampos, Griselda Asuncion
dc.contributor.authorCustódio, Luísa
dc.contributor.authorMereles, Laura
dc.contributor.authorÁvila, Rocio
dc.contributor.authorVillalba, Domitila
dc.contributor.authorLlano Obregon, Ismael
dc.contributor.authorSánchez Madsen, Fatima
dc.date.accessioned2025-10-04T09:11:15Z
dc.date.available2025-10-04T09:11:15Z
dc.date.issued2025-08-01
dc.description.abstractParasitic diseases caused by gastrointestinal nematodes (GIN) are considered important limiting factors for livestock production worldwide, as they significantly compromise animal welfare and increase production costs. For years, parasite control has relied exclusively on the use of synthetic drugs. Resistance of GIN to commercial anthelmintics has been increasingly reported throughout the world. Therefore, alternative approaches have emerged for controlling GIN in farm animals, including the exploration of plants with bioactive potential. Tithonia diversifolia can be harvested year-round, and all parts of the plant have been used in folk medicine for a wide range of diseases. This study evaluated the in vitro antioxidant properties of water and 70% aqueous acetone extracts of T. diversifolia aerial parts, including leaves, branches, and flowers, using radical-based methods, and assessed its anthelmintic potential through a parasite model, employing the egg hatching assay (EHA) with water extracts. Additionally, the total polyphenolic content of the extracts was determined. These findings highlight T. diversifolia as a promising natural source of antioxidant and anthelmintic compounds.eng
dc.description.sponsorshipCEECIND/00425/2017
dc.identifier.doi10.3791/67760
dc.identifier.issn1940-087X
dc.identifier.urihttp://hdl.handle.net/10400.1/27791
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMyJove Corporation
dc.relationAlgarve Centre for Marine Sciences
dc.relationAlgarve Centre for Marine Sciences
dc.relationCentre for Marine and Environmental Research
dc.relation.ispartofJournal of Visualized Experiments
dc.rights.uriN/A
dc.titleEvaluation of antioxidant and anthelmintic properties of tithonia diversifolia extracts against gastrointestinal nematode eggs using in vitro assayseng
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleCentre for Marine and Environmental Research
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04326%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0101%2F2020/PT
oaire.citation.endPage16
oaire.citation.issue222
oaire.citation.startPage10
oaire.citation.titleJournal of Visualized Experiments
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCustódio
person.givenNameLuísa
person.identifier.ciencia-id791B-C560-AEA2
person.identifier.orcid0000-0003-4338-7703
person.identifier.ridM-6101-2013
person.identifier.scopus-author-id15831018900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublicationf9cfed0f-6b67-413e-988c-ac7397183471
relation.isAuthorOfPublication.latestForDiscoveryf9cfed0f-6b67-413e-988c-ac7397183471
relation.isProjectOfPublicationfafa76a6-2cd2-4a6d-a3c9-772f34d3b91f
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relation.isProjectOfPublication.latestForDiscoveryfafa76a6-2cd2-4a6d-a3c9-772f34d3b91f

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