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Multifocal infantile haemangioma: a diagnostic challenge

dc.contributor.authorTorres, Erica
dc.contributor.authorRosa, JoĂŁo
dc.contributor.authorLeaute-Labreze, Christine
dc.contributor.authorSoares-de-Almeida, Luis
dc.date.accessioned2017-04-07T15:56:28Z
dc.date.available2017-04-07T15:56:28Z
dc.date.issued2016-07
dc.description.abstractWe describe a case of a newborn who presented with multiple dark red macules that developed into red-to-purple papules associated with thrombocytopaenia. Abdominal ultrasound showed multiple hyperechoic papules and nodules. Endothelial cells from a skin biopsy stained positively for endothelial cell glucose transporter 1, which was consistent with a diagnosis of multifocal infantile haemangioma. At the age of 2?months, the child developed intestinal bleeding and anaemia. Upper and lower endoscopies showed no intestinal haemangiomas. Oral treatment with propranolol (3?mg/kg/day) resulted in complete involution of the skin and hepatic haemangiomas over the period of treatment, which lasted until the child was aged 15?months. This is a rare case of multifocal cutaneous haemangioma with hepatic and probable intestinal involvement, successfully treated with propranolol.
dc.identifier.doi10.1136/bcr-2016-214827
dc.identifier.urihttp://hdl.handle.net/10400.1/9424
dc.language.isoeng
dc.peerreviewedyes
dc.publisherBMJ Publishing Group
dc.relation.isbasedonMEDLINE:27317759
dc.titleMultifocal infantile haemangioma: a diagnostic challenge
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBMJ Case Reports
oaire.citation.volume2016
rcaap.rightsopenAccess
rcaap.typearticle

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