Repository logo
 
Publication

Dietary antioxidant supplementation promotes growth in senegalese sole postlarvae

2020Journal article Open access
Simple item page
dc.contributor.authorXavier, Maria J
dc.contributor.authorEngrola, Sofia
dc.contributor.authorConceição, Luis E C
dc.contributor.authorManchado, Manuel
dc.contributor.authorCarballo, Carlos
dc.contributor.authorGonçalves, Renata
dc.contributor.authorColen, R.
dc.contributor.authorFigueiredo, Vera
dc.contributor.authorValente, Luisa M P
dc.date.accessioned2020-12-11T18:19:43Z
dc.date.available2020-12-11T18:19:43Z
dc.date.issued2020
dc.description.abstractSomatic growth is a balance between protein synthesis and degradation, and it is largely influenced by nutritional clues. Antioxidants levels play a key role in protein turnover by reducing the oxidative damage in the skeletal muscle, and hence promoting growth performance in the long-term. In the present study, Senegalese sole postlarvae (45 days after hatching, DAH) were fed with three experimental diets, a control (CTRL) and two supplemented with natural antioxidants: curcumin (CC) and grape seed (GS). Trial spanned for 25 days and growth performance, muscle cellularity and the expression of muscle growth related genes were assessed at the end of the experiment (70 DAH). The diets CC and GS significantly improved growth performance of fish compared to the CTRL diet. This enhanced growth was associated with larger muscle cross sectional area, with fish fed CC being significantly different from those fed the CTRL. Sole fed the CC diet had the highest number of muscle fibers, indicating that this diet promoted muscle hyperplastic growth. Although the mean fiber diameter did not differ significantly amongst treatments, the proportion of large-sized fibers (>25 μm) was also higher in fish fed the CC diet suggesting increased hypertrophic growth. Such differences in the phenotype were associated with a significant up-regulation of the myogenic differentiation 2 (myod2) and the myomaker (mymk) transcripts involved in myocyte differentiation and fusion, respectively, during larval development. The inclusion of grape seed extract (GS diet) resulted in a significant increase in the expression of myostatin1. These results demonstrate that both diets (CC and GS) can positively modulate muscle development and promote growth in sole postlarvae. This effect is more prominent in CC fed fish, where increased hyperplastic and hypertrophic growth of the muscle was associated with an upregulation of myod2 and mymk genes.pt_PT
dc.description.sponsorshipFCT: IF/00482/2014/CP1217/CT0005; UIDB/04326/2020; VALORMAR (ref. 024517) through Compete 2020, Lisboa 2020, CRESC Algarve 2020, Portugal 2020 and the European Union’s ERDF, and IFAPA project RTA2017-00054-C03-01 funded from MCIU/AEI/FEDER, UE.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3389/fphys.2020.580600pt_PT
dc.identifier.issn1664-042X
dc.identifier.urihttp://hdl.handle.net/10400.1/14903
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontiers Mediapt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMuscle growthpt_PT
dc.subjectSenegalese solept_PT
dc.subjectDietary antioxidantspt_PT
dc.subjectMyogenesispt_PT
dc.subjectProtein degradationpt_PT
dc.titleDietary antioxidant supplementation promotes growth in senegalese sole postlarvaept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage580600pt_PT
oaire.citation.titleFrontiers in Physiologypt_PT
oaire.citation.volume11pt_PT
person.familyNameEngrola
person.familyNamePontes Barbosa Colen
person.givenNameSofia
person.givenNameRita Isabel
person.identifier237846
person.identifier.ciencia-idA610-29E7-9B83
person.identifier.ciencia-idF113-B354-F356
person.identifier.orcid0000-0002-5244-5541
person.identifier.orcid0000-0001-7104-1844
person.identifier.ridA-2485-2012
person.identifier.scopus-author-id8669620600
person.identifier.scopus-author-id55323905000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication51be5a20-df9c-4a90-85eb-51d779642caa
relation.isAuthorOfPublication6aa7f225-0c1b-4d34-aede-b0e1ef925083
relation.isAuthorOfPublication.latestForDiscovery51be5a20-df9c-4a90-85eb-51d779642caa

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
fphys-11-580600.pdf
Size:
769.12 KB
Format:
Adobe Portable Document Format
Download

Collections

CCM2-Artigos (em revistas ou actas indexadas)