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A microelectrode impedance method to measure interaction of cells

dc.contributor.authorGomes, Henrique L.
dc.contributor.authorLeite, Ricardo
dc.contributor.authorAfonso, R.
dc.contributor.authorStallinga, Peter
dc.contributor.authorCancela, M. Leonor
dc.date.accessioned2015-06-26T14:18:47Z
dc.date.available2015-06-26T14:18:47Z
dc.date.issued2004
dc.description.abstractAn impedance method was developed to determine how immune system cells (hemocyte) interact with intruder cells (parasites). When the hemocyte cells interact with the parasites, they cause a defensive reaction and the parasites start to aggregate in clusters. The level of aggregation is a measure of the host-parasite interaction, and provides information about the efficiency of the immune system response. The cell aggregation is monitored using a set of microelectrodes. The impedance spectrum is measured between each individual microelectrode and a large reference electrode. As the cells starts to aggregate and settle down towards the microelectrode array the impedance of the system is changed. It is shown that the system impedance is very sensitive to the level of cell aggregation and can be used to monitor in real time the interaction between hemocyte cells and parasites.
dc.identifier.doihttps://dx.doi.org/10.1109/ICSENS.2004.1426344
dc.identifier.isbn0-7803-8692-2
dc.identifier.issn1930-0395
dc.identifier.otherAUT: PJO01566; HGO00803; LCA00739;
dc.identifier.urihttp://hdl.handle.net/10400.1/6637
dc.language.isoeng
dc.peerreviewedyes
dc.publisherIEEE
dc.relation.isbasedonP-000-DGY
dc.relation.ispartofIEEE Sensors
dc.titleA microelectrode impedance method to measure interaction of cells
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceVienna, Austria
oaire.citation.endPage1013
oaire.citation.startPage1011
oaire.citation.titleProceedings of IEEE Sensors 2004
oaire.citation.titleIEEE Sensors 2004 Conference
oaire.citation.volume2
person.familyNameGomes
person.familyNameLeite
person.familyNameAfonso
person.familyNameStallinga
person.familyNameCancela
person.givenNameHenrique Leonel
person.givenNameRicardo
person.givenNameRicardo
person.givenNamePeter
person.givenNameM. Leonor
person.identifier447622
person.identifier2477494
person.identifier.ciencia-idF115-256E-C84D
person.identifier.ciencia-idC917-2333-5797
person.identifier.orcid0000-0003-3664-4740
person.identifier.orcid0000-0002-9622-3895
person.identifier.orcid0000-0002-3884-9312
person.identifier.orcid0000-0002-9581-6875
person.identifier.orcid0000-0003-3114-6662
person.identifier.ridB-3389-2008
person.identifier.scopus-author-id7005305880
person.identifier.scopus-author-id8362650900
person.identifier.scopus-author-id6701332987
rcaap.rightsrestrictedAccess
rcaap.typeconferenceObject
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