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Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases

dc.contributor.authorParente Carvalho, Catia
dc.contributor.authorNorouzy, Amir
dc.contributor.authorRibeiro, Vera
dc.contributor.authorNau, Werner M.
dc.contributor.authorPischel, Uwe
dc.date.accessioned2018-12-07T14:53:40Z
dc.date.available2018-12-07T14:53:40Z
dc.date.issued2015-03
dc.description.abstractCucurbiturils (CB6 and CB7) were shown to inhibit the enzymatically catalyzed restriction of plasmids and linear DNA. This effect can be inverted by supramolecular masking of the macrocycles through competitive complexation with polyamines. These experiments provide supramolecular control of biocatalytic processes.
dc.description.sponsorshipSpanish MINECO [CTQ2011-28390]; FEDER; COST [CM1005]; DFG [NA-686/5]; Portuguese FCT [SFRH/BD/81628/2011, PEst-OE/EQB/LA0023/2013]
dc.identifier.doi10.1039/c4ob02122c
dc.identifier.issn1477-0520
dc.identifier.issn1477-0539
dc.identifier.urihttp://hdl.handle.net/10400.1/11632
dc.language.isoeng
dc.peerreviewedyes
dc.publisherRoyal Soc Chemistry
dc.subjectMolecular Containers
dc.subjectAmino-Acids
dc.subjectSynthetic Receptor
dc.subjectMass-Spectrometry
dc.subjectPk(A) Shifts
dc.subjectPeptides
dc.subjectBinding
dc.subjectRecognition
dc.subjectDrugs
dc.subjectThermodynamics
dc.titleCucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F81628%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PEst-OE%2FEQB%2FLA0023%2F2013/PT
oaire.citation.endPage2869
oaire.citation.issue10
oaire.citation.startPage2866
oaire.citation.titleOrganic & Biomolecular Chemistry
oaire.citation.volume13
oaire.fundingStreamSFRH
oaire.fundingStream3599-PPCDT
person.familyNameRibeiro
person.givenNameVera
person.identifier.ciencia-id3411-732A-B7FB
person.identifier.orcid0000-0002-9697-7830
person.identifier.ridG-3783-2011
person.identifier.scopus-author-id7006349364
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
rcaap.typearticle
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relation.isAuthorOfPublication.latestForDiscovery3f188970-86bb-4815-afd8-e5e70f922fd9
relation.isProjectOfPublication97082a70-0715-4f98-bcaf-16978991b918
relation.isProjectOfPublication89fcacba-95e1-424f-aee5-1a0bdc3d7303
relation.isProjectOfPublication.latestForDiscovery89fcacba-95e1-424f-aee5-1a0bdc3d7303

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