Repository logo
 
Publication

Antimicrobial activity, cytotoxicity and intracellular growth inhibition of Portuguese Thymus essential oils

2011Journal article Open access
Simple item page
dc.contributor.authorDandlen, S. A.
dc.contributor.authorLima, A. S.
dc.contributor.authorMendes, M. D.
dc.contributor.authorMiguel, Maria Graça
dc.contributor.authorFaleiro, Leonor
dc.contributor.authorSousa, M. J.
dc.contributor.authorPedro, L. G.
dc.contributor.authorBarroso, J. G.
dc.contributor.authorFigueiredo, A. C.
dc.date.accessioned2015-06-15T14:53:36Z
dc.date.available2015-06-15T14:53:36Z
dc.date.issued2011
dc.description.abstractThyme essential oils are well recognized by their excellent biological activities and the antimicrobial activity of Portuguese thyme essential oils has been investigated with promising results, particularly against food borne pathogens. In this study the potential antimicrobial activity of the essential oils of five species of Thymus (Lamiaceae), namely Th. caespititius Brot., Th. camphoratus Hoffmanns. & Link, Th. capitellatus Hoffmanns. & Link., Th. carnosus Boiss. and Th. zygis L. was evaluated against Candida albicans, Haemophilus influenza, Helicobacter pylori, Listeria monocytogenes, Salmonella enterica and Streptococcus pneumoniae. H. pylori strains were the most susceptible bacteria, particularly to the essential oils of Th. caespititius (Planalto Central), Th. zygis (Rebordaos) and Th. caespititius (Pico) which minimum inhibitory concentration (MIC) values ranged from 0.05 to 0.08 mg. mL(-1). Th. caespititius essential oil from Planalto Central or its main component, carvacrol significantly (p<0.05) inhibited the intracellular growth of H. pylori, and showed no citotoxicity to the gastric cell line. Our results suggest the potential of this essential oil and its main component as a promising tool as anti-Helicobacter agent potentiating the eradication of this important gastroduodenal pathogen.
dc.identifier.doihttps://dx.doi.org/10.1590/S0102-695X2011005000155
dc.identifier.issn0102-695X
dc.identifier.otherAUT: MFA00238; MGM00322;
dc.identifier.urihttp://hdl.handle.net/10400.1/6351
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSociedade Brasileira de Farmacognosia
dc.relation.isbasedonP-002-K0Y
dc.titleAntimicrobial activity, cytotoxicity and intracellular growth inhibition of Portuguese Thymus essential oils
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1024
oaire.citation.issue6
oaire.citation.startPage1012
oaire.citation.titleRevista Brasileira de Farmacognosia
oaire.citation.volume21
person.familyNameMiguel
person.familyNameFaleiro
person.givenNameMaria da Graça
person.givenNameMaria Leonor
person.identifier252666
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.ciencia-id281D-5E01-F09A
person.identifier.orcid0000-0003-2507-4228
person.identifier.orcid0000-0002-3878-6948
person.identifier.scopus-author-id35562054500
person.identifier.scopus-author-id6507927018
rcaap.rightsopenAccess
rcaap.typearticle
relation.isAuthorOfPublication2507350f-9e60-4d4a-a096-53e58d93549c
relation.isAuthorOfPublication5361e29a-3b79-4ce8-9f87-0c667d60588d
relation.isAuthorOfPublication.latestForDiscovery5361e29a-3b79-4ce8-9f87-0c667d60588d

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Antimicrobial activity, cytotoxicity and intracellular growth inhibition of Portuguese Thymus essential oils.pdf
Size:
929.64 KB
Format:
Adobe Portable Document Format
Download

Collections

FCT2-Artigos (em revistas ou actas indexadas)