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Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet

2017-01Journal article Restricted access
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dc.contributor.authorGoncalves, Sandra
dc.contributor.authorMoreira, Elsa
dc.contributor.authorGrosso, C.
dc.contributor.authorAndrade, Paula B.
dc.contributor.authorValentao, Patricia
dc.contributor.authorRomano, Anabela
dc.date.accessioned2018-12-07T14:53:06Z
dc.date.available2018-12-07T14:53:06Z
dc.date.issued2017-01
dc.description.abstractThe antioxidant and enzyme inhibitory properties of methanolic extracts from four aromatic plants used in traditional medicine and food [Calamintha nepeta (L.) Savi subsp. nepeta, Helichrysum italicum subsp. picardii Franco, Mentha spicata L. and Origanum vulgare subsp. virens (Hoffmanns. & Link) Bonnier & Layens] were evaluated. The extract from O. vulgare exhibited the strongest DPPH (IC50 of 4.65 +/- 0.12 mu g/ml) and ABTS (1479.56 +/- 12.29 mu mol(TE)/g(extract)) scavenging capacities, as well as the largest ferric reducing ability (1746.76 +/- 45.11 mu mol(AAE)/g(extract)). This extract also showed the highest total phenolic content (1597.20 +/- 24.10 mu mol(GAE)/g(extract)) and although HPLC-DAD analysis revealed rosmarinic acid as the main compound of the extract, other compounds seem to be involved in the antioxidant activity. Furthermore, the extract from H. italicum, which was found to be rich in caffeoylquinic and dicaffeoylquinic acids and in pinocembrin, showed the highest inhibitory potential against acetylcholinesterase, tyrosinase and alpha-glucosidase. Overall, the results obtained validate the usefulness of the studied plants as valuable sources of natural agents beneficial for human health.
dc.description.sponsorshipEuropean Union; National Funds (FCT/MEC, Fundacao para a Ciencia e Tecnologia/Ministerio da Educacao e Ciencia) [UID/QUI/50006/2013]; Norte Portugal Regional Operational Programme; European Regional Development Fund (ERDF) [NORTE-01-0145-FEDER-000024]; FCT [SFRH/BPD/84112/2012, IF/01332/2014]
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1007/s13197-016-2453-z
dc.identifier.issn0022-1155
dc.identifier.issn0975-8402
dc.identifier.urihttp://hdl.handle.net/10400.1/11352
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer India
dc.relationINVESTIGATION OF WILD EDIBLE PLANTS AND AGRO-PRODUCTS OF THE ALGARVE REGION AS SOURCES OF BIOACTIVE AND HEALTH-PROMOTING PHYTOCHEMICALS
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectIn-Vitro
dc.subjectTyrosinase inhibitors
dc.subjectKey enzymes
dc.subjectAlzheimers-disease
dc.subjectAlpha-glucosidase
dc.subjectOxidative stress
dc.subjectL.
dc.subjectPolyphenols
dc.subjectCapacity
dc.subjectLamiaceae
dc.titlePhenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleINVESTIGATION OF WILD EDIBLE PLANTS AND AGRO-PRODUCTS OF THE ALGARVE REGION AS SOURCES OF BIOACTIVE AND HEALTH-PROMOTING PHYTOCHEMICALS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F84112%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT
oaire.citation.endPage227
oaire.citation.issue1
oaire.citation.startPage219
oaire.citation.titleJournal of Food Science and Technology-Mysore
oaire.citation.volume54
oaire.fundingStream5876
person.familyNameGonçalves
person.familyNameRomano
person.givenNameSandra
person.givenNameAnabela
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccess
rcaap.typearticle
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relation.isAuthorOfPublicatione3343b60-17d3-4f5e-a2bf-06f26da69206
relation.isAuthorOfPublication.latestForDiscoverya8b335b2-45cc-4578-89b0-153273014280
relation.isProjectOfPublication1a492594-2e36-49a0-a462-78fc1b6cb24c
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