Is preoperative chemosensitivity associated with improved outcomes in locally advanced gastric cancer? A multicentric retrospective real-world study

Perioperative chemotherapy (PCT) is the standard of care for locally advanced gastric cancer (LAGC) in western countries. However, less than 60% of patients complete the adjuvant part of treatment due to postoperative complications, toxicity and disease progression (DP). This study aim is to evaluate if preoperative chemosensitivity (POCS) is associated with improved overall survival (OS) and disease free survival (DFS).