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Plant species of Sub-Family Valerianaceae—A review on its effect on the Central Nervous System

dc.contributor.authorDas, Gitishree
dc.contributor.authorShin, Han-Seung
dc.contributor.authorTundis, Rosa
dc.contributor.authorGonçalves, Sandra
dc.contributor.authorTantengco, Ourlad Alzeus G.
dc.contributor.authorCampos, Maria G.
dc.contributor.authorAcquaviva, Rosaria
dc.contributor.authorMalfa, Giuseppe Antonio
dc.contributor.authorRomano, Anabela
dc.contributor.authorRobles, Joyce Ann H.
dc.contributor.authorClores, Mariel Q.
dc.contributor.authorPatra, Jayanta-Kumar
dc.date.accessioned2021-05-27T09:24:07Z
dc.date.available2021-05-27T09:24:07Z
dc.date.issued2021-04-22
dc.date.updated2021-05-24T15:03:45Z
dc.description.abstractValerianaceae, the sub-family of Caprifoliaceae, contains more than 300 species of annual and perennial herbs, worldwide distributed. Several species are used for their biological properties while some are used as food. Species from the genus Valeriana have been used for their antispasmodic, relaxing, and sedative properties, which have been mainly attributed to the presence of valepotriates, borneol derivatives, and isovalerenic acid. Among this genus, the most common and employed species is Valerianaofficinalis. Although valerian has been traditionally used as a mild sedative, research results are still controversial regarding the role of the different active compounds, the herbal preparations, and the dosage used. The present review is designed to summarize and critically describe the current knowledge on the different plant species belonging to Valerianaceae, their phytochemicals, their uses in the treatment of different diseases with particular emphasis on the effects on the central nervous system. The available information on this sub-family was collected from scientific databases up until year 2020. The following electronic databases were used: PubMed, Scopus, Sci Finder, Web of Science, Science Direct, NCBI, and Google Scholar. The search terms used for this review included Valerianaceae, Valeriana, Centranthus, Fedia, Patrinia, Nardostachys, Plectritis, and Valerianella, phytochemical composition, in vivo studies, Central Nervous System, neuroprotective, antidepressant, antinociceptive, anxiolytic, anxiety, preclinical and clinical studies.pt_PT
dc.description.sponsorshipUIDB/05183/2020, DL 57/2016/CP1361/CT0022, UIDB/00313/2020pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPlants 10 (5): 846 (2021)pt_PT
dc.identifier.doi10.3390/plants10050846pt_PT
dc.identifier.eissn2223-7747
dc.identifier.urihttp://hdl.handle.net/10400.1/15507
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectValerianaceaept_PT
dc.subjectAntidepressantpt_PT
dc.subjectAnxiolyticpt_PT
dc.subjectBiological activitiespt_PT
dc.subjectClinical studiespt_PT
dc.subjectMyorelaxantpt_PT
dc.subjectPhytochemicalspt_PT
dc.subjectSedativept_PT
dc.subjectValerianpt_PT
dc.titlePlant species of Sub-Family Valerianaceae—A review on its effect on the Central Nervous Systempt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue5pt_PT
oaire.citation.startPage846pt_PT
oaire.citation.titlePlantspt_PT
oaire.citation.volume10pt_PT
person.familyNameGonçalves
person.familyNameRomano
person.givenNameSandra
person.givenNameAnabela
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa8b335b2-45cc-4578-89b0-153273014280
relation.isAuthorOfPublicatione3343b60-17d3-4f5e-a2bf-06f26da69206
relation.isAuthorOfPublication.latestForDiscoverye3343b60-17d3-4f5e-a2bf-06f26da69206

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