Publication
An EXAFS approach to the study of polyoxometalate–proteiniInteractions: the case of decavanadate–actin
| dc.contributor.author | Marques, M. P. M. | |
| dc.contributor.author | Gianolio, Diego | |
| dc.contributor.author | Ramos, Susana | |
| dc.contributor.author | Carvalho, Luís E. A. B. | |
| dc.contributor.author | Aureliano, M. | |
| dc.date.accessioned | 2017-12-21T09:49:47Z | |
| dc.date.available | 2017-12-21T09:49:47Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Decavanadate−actin interactions were studied by EXAFS and XANES, allowing us to simultaneously probe, for the first time, all vanadium species in the system. V10 interacts with G-actin (at its ATP binding site), a V−SCys coordination having been verified along with oxidovanadium formation. V10’s interplay with F-actin was found to be weak and occur via a different mechanism. These results are relevant for understanding V10’s biological roles, at a molecular level, aiming at potential pharmacological applications. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.1021/acs.inorgchem.7b01018 | pt_PT |
| dc.identifier.issn | 0020-1669 | |
| dc.identifier.other | AUT: MAA01296; | |
| dc.identifier.uri | http://hdl.handle.net/10400.1/10268 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | American Chemical Society | pt_PT |
| dc.relation.publisherversion | http://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.7b01018 | pt_PT |
| dc.subject | Decavanadate | pt_PT |
| dc.subject | Actin | pt_PT |
| dc.title | An EXAFS approach to the study of polyoxometalate–proteiniInteractions: the case of decavanadate–actin | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 10903 | pt_PT |
| oaire.citation.issue | 18 | pt_PT |
| oaire.citation.startPage | 10893 | pt_PT |
| oaire.citation.title | Inorganic Chemistry | pt_PT |
| oaire.citation.volume | 56 | pt_PT |
| person.familyName | Aureliano | |
| person.givenName | Manuel | |
| person.identifier | 584146 | |
| person.identifier.ciencia-id | AA14-3490-DC5E | |
| person.identifier.orcid | 0000-0003-4858-3201 | |
| person.identifier.rid | I-3283-2012 | |
| person.identifier.scopus-author-id | 6603412860 | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | bb413661-7edd-4b57-8338-33889cfd05db | |
| relation.isAuthorOfPublication.latestForDiscovery | bb413661-7edd-4b57-8338-33889cfd05db |