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Femoral cortical bone in a Portuguese reference skeletal collection

dc.contributor.authorCurate, Francisco
dc.contributor.authorCunha, Eugenia
dc.date.accessioned2019-11-20T15:07:53Z
dc.date.available2019-11-20T15:07:53Z
dc.date.issued2017
dc.description.abstractThis study aims to investigate patterns of femoral cortical bone fragility with age (at death) and to evaluate its associations with sex and bone mineral density. Radiogrammetric parameters of the femur and bone mineral density at the proximal femur were assessed in an adult sample (N=98) from the Coimbra Identified Skeletal Collection (Portugal). Diaphysis total width (DTW), femoral cortical index (FEMCI) and bone mineral density (BMD) are significantly higher in males, while medullary width (MW) is not statistically different between sexes. Cortical bone parameters of the femoral diaphysis are associated with age only in women, whereas BMD decreases with age in both sexes. The evaluation of femoral cortical bone reveals sex-specific trajectories of endosteal bone loss and periosteal apposition, stemming from sexual differences in the rate and pattern of bone loss, and in bone size. In females, endocortical bone loss rises with age, particularly in peri- and postmenopausal years, decelerating later in life. Concomitantly, accretion of bone in the subperiosteal surface persists throughout adulthood - partially offsetting bone fragility in women. Strength in the femoral mid diaphysis appears to be pre served throughout most of the life course in both sexes.
dc.description.sponsorshipPortuguese Foundation for Science and Technology [SFRH/BPD/74015/2010]
dc.identifier.doi10.14195/2182-7982_34_5
dc.identifier.issn0870-0990
dc.identifier.issn2182-7982
dc.identifier.urihttp://hdl.handle.net/10400.1/13264
dc.language.isoeng
dc.peerreviewedyes
dc.publisherCoimbra Univ Press
dc.subjectMetacarpal radiogrammetry
dc.subjectPeriosteal apposition
dc.subjectMedieval population
dc.subjectAdult bone
dc.subjectAge
dc.subjectOsteoporosis
dc.subjectWomen
dc.subjectSex
dc.subjectStrength
dc.subjectIndex
dc.titleFemoral cortical bone in a Portuguese reference skeletal collection
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F74015%2F2010/PT
oaire.citation.endPage109
oaire.citation.startPage91
oaire.citation.titleAntropologia Portuguesa
oaire.citation.volume34
oaire.fundingStreamSFRH
person.familyNameTaborda Curate
person.givenNameJosé Francisco
person.identifierhttps://scholar.google.pt/citations?user=rG909IQAAAAJ&hl=pt-PT
person.identifier.ciencia-idEF1B-4B08-5982
person.identifier.orcid0000-0002-0480-209X
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
rcaap.typearticle
relation.isAuthorOfPublication255b6420-8d4b-438d-b232-6ba3d1a1248c
relation.isAuthorOfPublication.latestForDiscovery255b6420-8d4b-438d-b232-6ba3d1a1248c
relation.isProjectOfPublication3c733ef8-a5e9-48a2-803a-049ada08b4de
relation.isProjectOfPublication.latestForDiscovery3c733ef8-a5e9-48a2-803a-049ada08b4de

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