Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/2542
Título: Inhibitory activity of plumbagin produced by Drosera intermedia on food spoilage fungi
Autor: Grevenstuk, Tomás
Gonçalves, Sandra
Domingos, Telma
Quintas, Célia
van der Hooft, Justin J. J.
Vervoort, Jacques
Romano, Anabela
Palavras-chave: In vitro culture
Minimum inhibitory concentration
Data: 2012
Editora: Wiley
Citação: Grevenstuk, Tomas; Gonçalves, Sandra; Domingos, Telma; Quintas, Celia; van der Hooft, Justin J. J.; Vervoort, Jacques; Romano, Anabela. Inhibitory activity of plumbagin produced by Drosera intermedia on food spoilage fungi, Journal of the Science of Food and Agriculture, 92, 8, 1638-1642, 2012
Resumo: Background: The aim of this study was to investigate the growth-inhibiting efficacy of Drosera intermedia extracts (water, methanol and n-hexane) against four food spoilage yeasts and five filamentous fungi strains responsible for food deterioration and associated with mycotoxin production, in order to identify potential antimycotic agents. Results: The n-hexane extract showed a broad activity spectrum against all tested microorganisms, followed, in activity, by the methanol and water extracts. The major component of the n-hexane extract was purified using a solid-phase extraction column and identified as plumbagin. Results show that high-purity plumbagin can be produced from D. intermedia cultures following a simple and effective isolation procedure. A sample of purified plumbagin was tested against the same panel of microorganisms and high growth-inhibiting capacity was observed. Minimum inhibitory concentrations less than 2 μgmL−1 were obtained against the filamentous fungi. In the case of the species Aspergillus fumigatus, A. niger and A. flavus, activities comparable to miconazole were obtained. Conclusion: The results obtained provided evidence of the antimycotic activity of plumbagin, suggesting that D. intermedia could be the source of an interesting compound for the food industry as an alternative to preservatives.
Peer review: yes
URI: http://hdl.handle.net/10400.1/2542
DOI: http://dx.doi.org/ 10.1002/jsfa.5522
Aparece nas colecções:ISE2-Artigos (em revistas ou actas indexadas)

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
Grevenstuk et al 2012.pdf105,54 kBAdobe PDFVer/Abrir    Acesso Restrito. Solicitar cópia ao autor!

FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.