Browsing by Author "Lyoussi, B."
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- Anti-oxidant, Anti-inflammatory and Anti-proliferative Activities of Moroccan Commercial Essential OilsPublication . S, Azza; Lyoussi, B.; Megias, C.; Cortes Giraldo, I.; Vioque, J.; Figueiredo, A. C.; Miguel, Maria GraçaEssential oils (EO) possess antimicrobial, anti-inflammatory, insect repellent, anti-cancer, and antioxidant properties, among others. In the present work, the antioxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial EOs (Citrus aurantium, C. union, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare and Thymus vulgaris) were evaluated and compared with their main constituents. T. vulgaris EO showed the best free radicals scavenging capacity. This EO was also the most effective against lipid peroxidation along with C. limon and F. vulgare EOs. C. sempervirens EO was the most effective in scavenging NO free radicals, whereas C. limon EO showed the best chelating power. Not all of the major compounds of the EO were responsible for the whole activity of the EOs. T. vulgaris EO showed the best anti-proliferative activity against THP-1 cells in contrast to that of F. vulgare. The antioxidant and anti-inflammatory activities of the EOs were plant species dependent and not always attributable to the EOs main components. Nevertheless, the EOs anti-proliferative activities were more related to their main components, as with T. vulgaris, C. limon, E. globulus and C. sempervirens.
- Antioxidant activity of eight hydrosols from MoroccoPublication . S, Azza; Lyoussi, B.; Miguel, Maria GraçaEssential oils from aromatic and medicinal plants have received particular attention as potential natural agents for food preservation and medicine. Nevertheless, much less attention has been given to the components which remain dissolved in the distillation water. To this fraction which is quite fragrant and strongly flavoured with values of pH ranging from 4.5-5.5 is called hydrosol. The antioxidant activity of hydrosols produced by an enterprise from Morocco from eight aromatic species (Pelargonium graveolens, Artemisia herba-alba, Cupressus atlantica, Ocimum basilicum, Juniperus phoenicea, Pinus pinaster, Marrubium vulgare and Hyssopus officinalis) was evaluated. Several methods were used: Thiobarbituric acid Reactive Species (TBARS), Trolox Equivalent Antioxidant Capacity (TEAC), hydroxyl and superoxide scavenging abilities. The results showed that in TBARS and superoxide scavenging ability, H. officinalis hydrosol revealed to be the most effective (IC50 = 136 mg mL-1 and IC50 = 2 mg mL-1, respectively). In the TEAC assay, M. vulgare was the most effective (IC50 = 72 mg mL-1), although H. officinalis also presented a good activity ((IC50 = 87 mg mL-1). A. herba-alba hydrosol presented the best capacity for scavenging hydroxyl free radical (IC50 = 95 mg mL-1). © 2012 Asian Network for Scientific Informatio.
- Antioxidant activity of some Morrocan hydrosolsPublication . S, Azza; Lyoussi, B.; Miguel, Maria GraçaEssential oils are used in Cosmetic, Perfumery, Food and Pharmaceutical Industries as flavours and/or medicines. However, part of the essential oil components that remains in the distillation water (hydrosol or distillate water) has been less studied both in chemical and biological terms. This research concerns the antioxidant activity, measured through several methods, of Lavandula officinalis L., Origanum majorana L., Rosmarinus officinalis L., Salvia officinalis L. and Thymus vulgaris L., Cinnamomum verum J. Presl. and Syzygium aromaticum (L.) Merrill and Perry hydrosols. The ability of hydrosols to prevent oxidation was checked by two main methods: prevention of lipid peroxidation through the measurement of malonaldehyde produced after degradation of hydroperoxides; and ability for scavenging free radicals including hydroxyl and superoxide anion radicals. The S. aromaticum and T. vulgaris hydrosols, predominantly constituted by eugenol and carvacrol, respectively, were the most effective as antioxidants, except for scavenging superoxide anion radical. In this case, L. officinalis hydrosol in which linalool prevailed was a stronger antioxidant. The worst hydrosol as antioxidant was that of S. officinalis, independent on the method checked.
- Antioxidant and Antiacetylcholinesterase Activities of Some Commercial Essential Oils and Their Major CompoundsPublication . S, Azza; Lyoussi, B.; Miguel, Maria GraçaThe commercial essential oils of Citrus aurantium L., Cupressus sempervirens L., Eucalyptus globulus Labill., Foeniculum vulgare Mill. and Thymus vulgaris L., isolated by steam distillation by a company of Morocco were evaluated in terms of in vitro antioxidant activity through several methods. In vitro acetylcholinesterase inhibitory activity was also determined. Citrus limon (L.) Burm. f. oil was also studied, but it was obtained by peel expression. The best antioxidant was T. vulgaris oil, independent of the method used, mainly due to the presence of the phenolic monoterpenes thymol and carvacrol, which when studied as single compounds also presented the best activities. Concerning the acetylcholinesterase inhibition activity, E. globulus was the most effective. Nevertheless its main components 1,8-cineole and limonene were not the most active, a feature that corresponded to delta-3-carene.
- Antioxidant, anti-inflammatory and anti-acetylcholinesterase activities of eleven extracts of Moroccan plantsPublication . Miguel, Maria Graça; Bouchmaa, N.; S, Azza; Gaamoussi, F.; Lyoussi, B.The capacity of ethanolic extracts of wHaloxylon scoparium Pomel, Corrigiola telephiifolia Pourr., Ammodaucus leucotrichus Cosson & Durieu subsp. leucotrichus, Chamaerops humilis L., Sideritis arborescens Salzm. ex Benth., Ammi visnaga (L.) Lam., Vitex agnus castus L., Retama raetam (Forssk.) Webb & Berthel., Berberis vulgaris L., Viscum album L., and Equisetum arvense L. from Morocco to prevent lipid peroxidation, scavenging free radicals, inhibiting lipoxygenase and acetylcholinesterase activities, were evaluated and compared to those reported in the literature. As far as we know, the present work was the first reporting on the antioxidant ability of S. arborescens. The results showed that Equisetum arvense and Sideritis arborescens (stems) possessed the highest concentrations of total phenols and flavonoids, respectively, and the extracts of Berberis vulgaris and Viscum album were the most promising as antioxidants as well as anti-inflammatory and acetylcholinesterase (AChE) inhibitors. In some cases, the activities of B. vulgaris extracts were not significantly different from those found for positive control (e.g. capacity for scavenging free radicals, and capacity for inhibiting AChE).
- Physicochemical characterization and antioxidant activity of 17 commercial Moroccan honeysPublication . AAZZA, Smail; Lyoussi, B.; Antunes, Maria Dulce; Miguel, Maria GraçaIn this study, 17 commercial honey samples from Morocco were analyzed. Four samples did not meet the international physicochemical standards due to high hydroxymethylfurfural content and low diastase activity. Phenol content varied from 163.82mg gallic acid equivalent (GAE)/kg in citrus honey to 923.70mg (GAE)/kg in thyme honey from Rachidia; flavonoid content ranged from 4.26mg quercetin equivalent (QE)/kg in citrus honey to 139.62mg QE/kg in black cumin honey. Black cumin honey had the highest peroxyl scavenging activity; oregano (from Zaraphyt) and thyme honeys (from Rachidia) had the highest ABTS (2,2'-azino-bis[ 3-ethylbenzothiazoline-6-sulphonic acid]) scavenging activity; and thyme honey (Saouira) had the highest NO scavenging capacity. The antioxidant activity of Moroccan honeys was correlated with the phenol, flavonoid, and melanoidin contents. Dark honeys had higher antioxidant activity than light honeys. Samples with high sodium levels had lower free radical scavenging activity. On the other hand, calcium and magnesium increased the ABTS and peroxyl scavenging capacity, respectively, of honey samples. According to cluster and discriminant analyses, the honey samples were grouped in three clusters with respect to the phenol, flavonoid, melanoidin, proline, mineral and sugar contents, and free radical scavenging capacity.
- Physicochemical Characterization and Antioxidant Activity of Commercial Portuguese HoneysPublication . AAZZA, Smail; Lyoussi, B.; Antunes, Maria Dulce; Miguel, Maria GraçaThe present study evaluated the physicochemical characteristics and antioxidant activity of 13 commercial honeys from diverse floral origin, produced in Portugal. The values of electrical conductivity of cardoon and pennyroyal honeys were superior to the maximum limits defined by European legislation. Citrus, strawberry tree, and 1 sample of lavender honeys had values of diastase activity below those determined by European legislation. Strawberry tree, pennyroyal, and cardoon honeys had the highest amounts of potassium that coincided with the highest electrical conductivity. Strawberry tree honey was the most effective as antioxidant along with cardoon and heather honeys. This ability was strongly correlated with the amounts of phenols and flavonoids and not with the levels of vitamin C or proline.