Browsing by Author "Pinto, Sandra"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Acessibilidade escolar: o caso da Escola Secundária Pinheiro e Rosa em FaroPublication . Pinto, Sandra; Pires Rosa, ManuelaA escola inclusiva defende que todos os alunos devem possuir os mesmos direitos e as mesmas igualdades de oportunidades, independentemente das suas dificuldades e características. Os paradigmas sociais e educativos mostram que a escola deve garantir o sucesso educativo de todos os seus alunos e a sua autonomia em termos de mobilidade. Neste contexto os fatores ambientais assumem uma importância relevante no modelo biológico-químico-social da deficiência. Há por isso que garantir que as escolas inclusivas sejam adaptadas às diversas necessidades dos alunos. No presente estudo, focaliza-se a atenção para os que utilizam cadeira de rodas para se deslocarem. Apresenta-se neste estudo uma proposta metodológica de análise e diagnóstico da acessibilidade física escolar, através da construção de parâmetros de desempenho, com base na legislação atualmente em vigor, o Decreto-lei nº 63/2006 de 8 de agosto. Esta metodologia foi aplicada a uma escola secundária localizada na cidade de Faro. O diagnóstico efetuado permitiu averiguar que a escola tem vindo a potenciar a acessibilidade aos seus edifícios e à sua envolvente, apesar de carecer de algumas melhorias arquitetónicas para a tornar plenamente acessível.
- Equidade social na acessibilidade aos espaços escolaresPublication . Pinto, Sandra; Pires Rosa, ManuelaThe concepts of inclusive education and school consider that all students should have the same rights and the same equality of opportunities, regardless their difficulties and characteristics. An analysis of the social and educational paradigms towards inclusive education shows that the school should adjust its educational practice to ensure the educational success of all students and their autonomy in terms of mobility. In this context it is assumed a great importance of environmental factors in the biological-chemical-social model of disability. Therefore one must ensure that inclusive schools are architecturally adapted to the diverse needs of students. This accessibility requirement to the built environment is internationally assumed by institutions and communities working towards an inclusive school. Building inclusive schools and societies requires that the design and rehabilitation of urban and built environment respect the principles of universal design by providing ‘ equitable use’e’, ‘flexible’, ‘intuitive’, ‘perceptible’, ‘low physical effort’, ‘tolerable’, and ‘well-dimensioned’ spaces for diverse users.
- New fluorescent probes based on gallium(III) corrole complexes for the recognition of hydrogen sulfide: a journey from solution to intracellular sitePublication . Santos, Carla I.M.; Santiago, Ana M.; Araújo, Ana R.L.; Pinto, Sandra; Agostinho, Rafaela; Simão, Sónia; Azevedo, Tomás Pais de; Antunes, Catarina; Faustino, M. Amparo F.; Araujo, Ines; Neves, M. Graça P.M.S.; Martinho, José M.G.; Maçôas, Ermelinda M.S.In this work, three fluorescent probes for detection of hydrogen sulfide (H2S) where prepared based on gallium (III) corrole complexes bearing nitro groups at beta-pyrrolic positions. Two of the compounds selected, the 3-nitro5,10,15- tris(pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-NO2) and the 3,17-dinitro-5,10,15-tris (pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-2NO2) present one and two nitro groups directly linked to the beta-pyrrolic position. The third compound, the (E)-3-(2-nitroprop-1-en-1-yl)-5,10,15-tris(pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-EtNO2), has a carbon-carbon double bond spacer between the corrole unit and the nitro group. All these derivatives were obtained from 5,10,15-tris(pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa). The precursor CGa and the derivative CGa-EtNO2 behaved as turn-OFF probes, while compound CGa-NO2 responded as a turn-ON probe in the presence of H2S in the pH range of 5-9. Mechanistic studies show that the interaction of H2S with the probes involves its coordination with gallium(III) and in some cases the reduction of the nitro group to a new aminated corrole. While the formation of the coordination complex with H2S is almost immediate, the kinetics of the reduction is slow. Interestingly, for CGaNO2 the two processes can be explored in a ratiometric sensing of H2S in a non-aqueous solution showing a good linearity over an extended concentration range (5-200 mu M). The response of the corroles to H2S in intracellular medium was studied in 2D cultured cells (HeLa).