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- Feature papers in BioChem, 2nd EditionPublication . Aureliano, Manuel; Ma, BuyongAs mentioned in the Editorial of the first edition of the Special Issue on “Feature Papers in BioChem”, biochemistry acts as a key cog in the “clock of the knowledge, permitting that wheels from several science areas move each other” [1]. Moreover, the understanding of life on earth is a perpetual topic in biochemistry, with boundaries dependent on the specificities of each time period and scientific environment [1]. Thus, following the first edition, this Special Issue on “Feature Papers in BioChem, 2nd Edition” still emphases interdisciplinary research in diverse and interconnected scientific areas, with a majority from molecular medicine, cell biology and of course biochemistry (Table 1). Among these scientific fields, a wide range of topics were addressed, as expressed by the diversity of the titles and keywords that can be found in each contribution.