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BONE GLA AND MATRIX GLA PROTEINS FROM THE SEABREAM, SPARUS AURATA: FUNCTION ON MINERALIZATION OF THE EXTRACELLULAR MATRIX FROM BONE, CARTILAGE AND SOFT TISSUES.

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Identification of a promoter element within the zebrafish Collagen X¿1 gene responsive to Runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2aA2
Publication . Simões, B.; Conceição, N.; S B Viegas, Carla; Pinto, Jorge; Gavaia, Paulo J.; Kelsh, R. N.; Cancela, Leonor
Type X collagen is a short chain collagen specifically expressed by hypertrophic chondrocytes during endochondral ossification. We report here the functional analysis of the zebrafish (Danio rerio) collagen Xa1 gene (colXa1) promoter with the identification of a region responsive to two isoforms of the runt domain transcription factor runx2.

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Funding agency

Fundação para a Ciência e a Tecnologia

Funding programme

PRAXIS XXI

Funding Award Number

PRAXIS XXI/BPD/18816/98

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