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Characterization of a sea bream (Sparus aurata) thyroid hormone receptor-ß clone expressed during embryonic and larval development

2001Journal article Restricted access
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dc.contributor.authorNowell, M. A.
dc.contributor.authorPower, Deborah
dc.contributor.authorCanario, Adelino V. M.
dc.contributor.authorLlewellyn, Lynda
dc.contributor.authorSweeney, Glen E.
dc.date.accessioned2014-05-14T12:25:08Z
dc.date.available2014-05-14T12:25:08Z
dc.date.issued2001
dc.date.updated2014-05-09T09:56:48Z
dc.description.abstractA clone encoding thyroid hormone receptor-b (TR-b) was isolated from a sea bream (Sparus aurata) ovary cDNA library. Sea bream (sb)TR-b is closely related to its counterparts from other vertebrates and, like them, preferentially binds T3 rather than T4. However, the putative sbTR-b protein contains a nine-amino-acid insert that is also present in the corresponding proteins from flounder and salmon but absent in TR-bs from zebrafish and terrestrial vertebrates. Semiquantitative RT–PCR analysis showed that sbTR-b transcripts begin to accumulate during gastrulation and increase markedly in quantity up to the period around hatch (ca. 40 h postfertilization) before declining slightly. In adult tissues, TR-b mRNA was present in approximately equal quantities in heart, intestine, brain, kidney, skeletal muscle, liver, and gill. The significance of the relatively strong expression of TR-b during sea bream embryogenesis is discussed.por
dc.identifier.citationNowell, M.A.; Power, D.M.; Canario, A.V.M.; Llewellyn, L.; Sweeney, G.E. Characterization of a Sea Bream (Sparus aurata) Thyroid Hormone Receptor-ß Clone Expressed during Embryonic and Larval Development, General and Comparative Endocrinology, 123, 1, 80-89, 2001.por
dc.identifier.doihttp://dx.doi.uri/10.1006/gcen.2001.7649
dc.identifier.issn0016-6480
dc.identifier.otherAUT: DPO00386; ACA00258;
dc.identifier.urihttp://hdl.handle.net/10400.1/3930
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAcademic Presspor
dc.titleCharacterization of a sea bream (Sparus aurata) thyroid hormone receptor-ß clone expressed during embryonic and larval developmentpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage89por
oaire.citation.issue1por
oaire.citation.startPage80por
oaire.citation.titleGeneral and Comparative Endocrinologypor
oaire.citation.volume123por
person.familyNamePower
person.familyNameCanario
person.givenNameDeborah Mary
person.givenNameAdelino
person.identifier143624
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.ciencia-id1F1E-D3B3-F804
person.identifier.orcid0000-0003-1366-0246
person.identifier.orcid0000-0002-6244-6468
person.identifier.ridC-7942-2009
person.identifier.scopus-author-id7101806760
person.identifier.scopus-author-id56568523700
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationc68f5ffb-63f6-4c70-8957-29e464fb59c0
relation.isAuthorOfPublication5f6e51ee-9113-469e-8b9e-f30f2d452521
relation.isAuthorOfPublication.latestForDiscoveryc68f5ffb-63f6-4c70-8957-29e464fb59c0

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