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Vanadate oligomer inhibition of passive and active Ca2+ translocation by the Ca2+ pump of sarcoplasmic reticulum

2000-05-30Journal article Restricted access
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dc.contributor.authorAureliano, M.
dc.date.accessioned2014-07-15T11:11:39Z
dc.date.available2014-07-15T11:11:39Z
dc.date.issued2000-05-30
dc.description.abstract‘Monovanadate’ containing mainly monomeric, dimeric and tetrameric vanadate species or ‘decavanadate’, containingmainlydecameric vanadate species inhibits the passive and the active efflux of Ca2+ through the sarcoplasmic reticulum calcium pump. When the efflux of Ca2+ by sarcoplasmic reticulum vesicles is not associated with ATP synthesis both vanadate solutions inhibit the passive efflux of Ca 2+. However, only ‘decavanadate’ exerts noticeable effects when the efflux of Ca2q is associated with ATP synthesis being the active efflux of Ca2+ almost completely inhibited by decameric species concentration as low as 40 microM.por
dc.identifier.issn0162-0134
dc.identifier.otherAUT: MAA01296
dc.identifier.urihttp://hdl.handle.net/10400.1/4776
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://ac.els-cdn.com/S0162013400000222/1-s2.0-S0162013400000222-main.pdf?_tid=0149b7ce-0c10-11e4-b78e-00000aacb35e&acdnat=1405422547_43667c8077cb759a319adb2504f76266por
dc.subjectDecavanadatepor
dc.subjectCalcium ATPasepor
dc.subjectSarcoplasmic reticulumpor
dc.titleVanadate oligomer inhibition of passive and active Ca2+ translocation by the Ca2+ pump of sarcoplasmic reticulumpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage147por
oaire.citation.issue1-2por
oaire.citation.startPage145por
oaire.citation.titleJournal of Inorganic Biochemistrypor
oaire.citation.volume80por
person.familyNameAureliano
person.givenNameManuel
person.identifier584146
person.identifier.ciencia-idAA14-3490-DC5E
person.identifier.orcid0000-0003-4858-3201
person.identifier.ridI-3283-2012
person.identifier.scopus-author-id6603412860
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationbb413661-7edd-4b57-8338-33889cfd05db
relation.isAuthorOfPublication.latestForDiscoverybb413661-7edd-4b57-8338-33889cfd05db

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