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Amentadione is a new modulating agent for osteoarthritis in an ex-vivo co-culture preclinical assay

2019Journal article Open access
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dc.contributor.authorAraujo, Nuna C. P.
dc.contributor.authorViegas, Carla
dc.contributor.authorPerrolas, Inês
dc.contributor.authorCosta, Rúben
dc.contributor.authorMagalhães, Joana
dc.contributor.authorBlanco, Francisco
dc.contributor.authorRamos, Acácio
dc.contributor.authorMiguel, Maria
dc.contributor.authorVermeer, Cees
dc.contributor.authorZubía, Eva
dc.contributor.authorSimes, Dina
dc.date.accessioned2020-07-27T14:48:03Z
dc.date.available2020-07-27T14:48:03Z
dc.date.issued2019
dc.description.abstractOsteoarthritis (OA) is a whole-joint disease where inflammation interplays with extracellular matrix mineralization in a cycle that leads to its degradation. The lack of effective preventing treatments and disease modifying agents, demands new therapeutic targets and development of effective drugs.pt_PT
dc.description.sponsorshipFCT: SFRH/BD/111824/2015pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1080/07853890.2018.1561895pt_PT
dc.identifier.issn0785-3890
dc.identifier.urihttp://hdl.handle.net/10400.1/14524
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAmentadione (YP)pt_PT
dc.subjectOsteoarthritis (OA)pt_PT
dc.subjectInflammationpt_PT
dc.subjectCalcificationpt_PT
dc.subjectCo-culturept_PT
dc.titleAmentadione is a new modulating agent for osteoarthritis in an ex-vivo co-culture preclinical assaypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04326%2F2013/PT
oaire.citation.conferencePlaceJoint Congress of 3rd International Congress of CiiEM Research and Innovation in Human and Health Sciences and the 3rd World Congress of the UNESCO Chair for Teaching and Research in Digital Anatomy Paris Descartespt_PT
oaire.citation.endPage43pt_PT
oaire.citation.issuesup1pt_PT
oaire.citation.startPage43pt_PT
oaire.citation.titleAnnals of Medicinept_PT
oaire.citation.volume51pt_PT
oaire.fundingStream5876
person.familyNameAraujo
person.familyNameViegas
person.familyNameCosta
person.familyNameMiguel
person.familyNameSimes
person.givenNameNuna
person.givenNameCarla
person.givenNameRúben
person.givenNameMaria da Graça
person.givenNameDina
person.identifier.ciencia-idC414-F596-EEC6
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.orcid0000-0002-7602-0150
person.identifier.orcid0000-0002-5765-3665
person.identifier.orcid0000-0002-3155-9005
person.identifier.orcid0000-0003-2507-4228
person.identifier.orcid0000-0002-5145-4753
person.identifier.ridN-8531-2013
person.identifier.ridN-6695-2014
person.identifier.ridN-2789-2014
person.identifier.scopus-author-id8656310300
person.identifier.scopus-author-id35562054500
person.identifier.scopus-author-id7201884723
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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