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Revisão do potencial toxicológico de excipientes com aplicação em dermocosmética
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Abstract(s)
A Dermocosmética é uma área farmacêutica em constante desenvolvimento, que gera muitos lucros para as empresas farmacêuticas ao mesmo tempo que exige um elevado investimento na introdução de novas formulações cosméticas a um ritmo capaz de satisfazer com eficácia a necessidade dos seus clientes. Em Portugal, o mercado de Dermocosmética representa cerca de 25% de mercado nas farmácias e parafarmácias do total de mercado de saúde e beleza.
Um produto cosmético define-se como qualquer substância ou mistura destinada a ser posta em contacto com as partes externas do corpo humano (epiderme, sistemas piloso e capilar, unhas, lábios, órgãos genitais externos) ou com os dentes e a mucosa bucal, tendo como objetivos, exclusiva ou principalmente, limpá-los, perfumá-los, modificar-lhes o aspeto, protegê-los, mantê-los em bom estado ou corrigir os odores corporais. Os cosméticos englobam um vasto espectro de produtos de várias categorias, abrangendo os produtos de higiene corporal, nomeadamente sabonetes, geles de banho, champôs, desodorizantes, pastas dentífricas e ainda, os produtos de beleza, como tintas capilares, vernizes e maquilhagem.
Nos últimos anos têm surgido estudos que avaliam a toxicidade de alguns ingredientes utilizados nas formulações cosméticas, quando utilizados pelo ser humano essencialmente na tentativa de dar resposta a dúvidas e preocupações que têm surgido a esse respeito. Algumas dessas substâncias são utilizadas nas formulações como conservantes (parabenos, triclosan, fenoxietanol, ftalatos, formaldeído, libertadores de formaldeído), antioxidantes, emolientes (óleos minerais, polietilenoglicol, silicones), tensioativos (dietanolamina, laurilsulfato do sódio). Ao mesmo tempo são cada vez mais procurados pelos consumidores produtos cosméticos cujos rótulos das embalagens contenham afirmações como “vegan”, “sem parabenos”, “sem ingredientes minerais”, “sem silicones”, “sem fenoxietanol”.
Esta dissertação pretende esclarecer o leitor sobre o potencial efeito tóxico que as substâncias anteriormente referidas podem ter para o ser humano.
Dermocosmetics is a pharmaceutical area in constant development, which generates many profits for pharmaceutical companies while requiring a high investment in the introduction of new cosmetic formulations at a pace capable of effectively satisfying the needs of their customers. In Portugal, the Dermocosmetics market represents about 25% of the total health and beauty market sold in pharmacies and parapharmacies. A cosmetic product is defined as any mixed substance intended to become in contact with the external parts of the human body (epidermis, hair and capillary systems, nails, lips, external genital organs) or with the teeth and oral mucosa, having as objectives, exclusively or mainly, to clean, protect, keep in good condition, modify the appearance, perfume the parts or correct body odors. Cosmetics encompass a wide spectrum of products from various categories, covering body care products, including soaps, shower gels, shampoos, deodorants, toothpastes and beauty products such as hair dyes, varnishes and make-up. In recent years, studies have emerged that assess the toxicity of some ingredients used in cosmetic formulations, when used by humans. Some of these substances are used in formulations such as preservatives (parabens, triclosan, phenoxyethanol, phthalates, formaldehyde, formaldehyde releasers), antioxidants, emollients (mineral oils, polyethylene glycol, silicones), surfactants (diethanolamine, sodium lauryl sulfate). At the same time, consumers are increasingly looking for skin care products whose packaging labels contain statements such as “vegan”, “no parabens”, “no mineral ingredients”, “no silicones”, “no phenoxyethanol”. This dissertation aims to clarify the reader about the potential toxic effects of the aforementioned substances on humans.
Dermocosmetics is a pharmaceutical area in constant development, which generates many profits for pharmaceutical companies while requiring a high investment in the introduction of new cosmetic formulations at a pace capable of effectively satisfying the needs of their customers. In Portugal, the Dermocosmetics market represents about 25% of the total health and beauty market sold in pharmacies and parapharmacies. A cosmetic product is defined as any mixed substance intended to become in contact with the external parts of the human body (epidermis, hair and capillary systems, nails, lips, external genital organs) or with the teeth and oral mucosa, having as objectives, exclusively or mainly, to clean, protect, keep in good condition, modify the appearance, perfume the parts or correct body odors. Cosmetics encompass a wide spectrum of products from various categories, covering body care products, including soaps, shower gels, shampoos, deodorants, toothpastes and beauty products such as hair dyes, varnishes and make-up. In recent years, studies have emerged that assess the toxicity of some ingredients used in cosmetic formulations, when used by humans. Some of these substances are used in formulations such as preservatives (parabens, triclosan, phenoxyethanol, phthalates, formaldehyde, formaldehyde releasers), antioxidants, emollients (mineral oils, polyethylene glycol, silicones), surfactants (diethanolamine, sodium lauryl sulfate). At the same time, consumers are increasingly looking for skin care products whose packaging labels contain statements such as “vegan”, “no parabens”, “no mineral ingredients”, “no silicones”, “no phenoxyethanol”. This dissertation aims to clarify the reader about the potential toxic effects of the aforementioned substances on humans.
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Keywords
Cosmético Segurança Ingrediente Toxicidade