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Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér

2012Journal article Restricted access
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dc.contributor.authorCosta, Patrícia
dc.contributor.authorGrosso, Clara
dc.contributor.authorGonçalves, Sandra
dc.contributor.authorAndrade, Paula B.
dc.contributor.authorValentão, Patrícia
dc.contributor.authorBernardo-Gil, Maria Gabriela
dc.contributor.authorRomano, Anabela
dc.date.accessioned2013-03-15T11:41:08Z
dc.date.available2013-03-15T11:41:08Z
dc.date.issued2012
dc.description.abstractThe chemical profiles of bioactive essential oil and extracts obtained by hydrodistillation (HD) and supercritical fluid extraction (SFE), respectively, from Lavandula viridis were compared. The SFE was performed at 40 C and at extraction pressures of 12 or 18 MPa in two different separators. Evaluation of the essential oil and SFE extracts by GC–FID and GC–IT–MS revealed that oxygen-containing monoterpenes were the major constituents in both cases, but there were important differences between the chemical profiles produced by the different extraction techniques. More compounds were isolated by HD but higher yields were achieved by SFE. Camphor was the main component identified in the essential oil (31.59 ± 1.32%), and in extracts from the first (1.61 ± 0.34%) and second SFE separators (22.48 ± 1.49%) at 12 MPa. In contrast, the first separator SFE extract at 18 MPa (heavy compounds) was dominated by myrtenol(5.38 ± 2.04%) and camphor (4.81 ± 1.93%), whereas the second separator SFE extract (volatiles) was dominated by verbenone (13.97 ± 5.27%). The essential oil and heavy compound extracts from the first separator possessed antioxidant and anti-cholinesterase activities. Our data show that phytochemicals from the aerial parts of L. viridis could be developed as natural antioxidant and anti-cholinesterase drugs, with particular applications in the symptomatic treatment of Alzheimer’s disease.por
dc.description.sponsorshipP. Costa, C. Grosso and S. Gonçalves acknowledge grants from the Portuguese Science and Technology Foundation (FCT) (SFRH/BD/63505/2009, SFRH/BPD/63922/2009 and SFRH/BPD/31534/2006, respectively). C. Grosso, P. B. Andrade and P. Valentão are grateful to FCT for grant no. PEst-C/EQB/LA0006/2011.por
dc.identifier.citationCosta P., Grosso C., Gonçalves S., Andrade P. B., Valentão P., Romano A 2012. Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér, Food Chemistry 135: 112–121por
dc.identifier.issn0308-8146
dc.identifier.otherAUT: ARO01015;
dc.identifier.urihttp://hdl.handle.net/10400.1/2583
dc.language.isoengpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0308814612007716por
dc.subjectLavandula viridispor
dc.subjectEssential oilpor
dc.subjectSFE extractspor
dc.subjectAntioxidantspor
dc.subjectAnti-cholinesterasepor
dc.subjectAlzheimer’s diseasepor
dc.titleSupercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hérpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage121por
oaire.citation.issue1por
oaire.citation.startPage112por
oaire.citation.titleFood Chemistrypor
oaire.citation.volume135por
person.familyNameGonçalves
person.familyNameRomano
person.givenNameSandra
person.givenNameAnabela
person.identifier.ciencia-id9F19-E3AE-2C59
person.identifier.ciencia-id8A18-7E9A-3B0E
person.identifier.orcid0000-0002-3038-4434
person.identifier.orcid0000-0002-7204-7428
person.identifier.ridM-6988-2017
person.identifier.scopus-author-id8583003200
person.identifier.scopus-author-id56249997600
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationa8b335b2-45cc-4578-89b0-153273014280
relation.isAuthorOfPublicatione3343b60-17d3-4f5e-a2bf-06f26da69206
relation.isAuthorOfPublication.latestForDiscoverye3343b60-17d3-4f5e-a2bf-06f26da69206

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