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Unravelling the potential of the medicinal halophyte Eryngium maritimum L.: In vitro inhibition of diabetes-related enzymes, antioxidant potential, polyphenolic profile and mineral composition

2019-01Journal article Restricted
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dc.contributor.authorPereira, Catarina
dc.contributor.authorLocatelli, M.
dc.contributor.authorInnosa, D.
dc.contributor.authorCacciagrano, F.
dc.contributor.authorPolesna, L.
dc.contributor.authorSantos, T. F.
dc.contributor.authorRodrigues, Maria João
dc.contributor.authorCustódio, L.
dc.date.accessioned2020-07-24T10:53:26Z
dc.date.available2020-07-24T10:53:26Z
dc.date.issued2019-01
dc.description.abstractThis work searched for the biotechnological potential and chemical characterisation of the medicinal halophyte Eryngium maritimum L. as source of bioactive natural products with enzymatic inhibitory properties and antioxidant capacity. With that aim, herbal formulations traditionally used in folk medicine, namely tisanes (infusions and decoctions) and tinctures, were prepared from four different anatomical organs (roots, stems, leaves and flowers) and assessed for in vitro inhibition of enzymes related with diabetes and for antioxidant potential. Phenolic fingerprinting and mineral contents were also assessed. Sea holly's tisanes, particularly from flowers and leaves, had the highest phenolic content although tinctures were comparatively richer considering the ingestion dosage. The main constituents identified were carvacrol, 2,3-dimethoxybenzoic acid, naringenin, catechin and t-cinnamic acid
dc.description.abstractfrom the several compounds identified, naringin, naringenin and 2,3-dimethoxybenzoic acid are here firstly described in the genus and epicatechin and carvacrol in the species. In all extracts, sodium was the most abundant mineral, followed by potassium, calcium and magnesium, pointing to possible nutritional applications of these beverages/tinctures asmacronutrients supplementary source. Sea holly's tinctures (stems, leaves and flowers) were capable of inhibiting dietary carbohydrate digestive enzymes (alpha-glucosidase and alpha-amylase) and had in vitro antioxidant potential, particularly flowers. Altogether, results highlight that sea holly extracts, especially tinctures from stems, leaves and flowers, could be a novel source of alpha-glucosidase and alpha-amylase inhibitors, antioxidant compounds and also phenolic and mineral constituents, thus suggesting they may be interesting to further explore as potential health-promoting herbal beverages, food additives or other products. (c) 2018 Published by Elsevier B.V. on behalf of SAAB.
dc.description.sponsorshipPortuguese Foundation for Science and Technology - FCTPortuguese Foundation for Science and Technology [CCMAR/Multi/04326/2013]
dc.description.sponsorshipPortuguese National Budget
dc.description.sponsorshipMIUR, University of Chieti-Pescara "G. d'Annunzio", Chieti, Italy
dc.description.sponsorshipFCT Investigator Programme [IF/00049/2012]
dc.description.sponsorshipFCTPortuguese Foundation for Science and Technology [SFRH/BD/94407/2013, SFRH/BD/116604/2016]
dc.identifier.doi10.1016/j.sajb.2018.06.013
dc.identifier.issn0254-6299
dc.identifier.issn1727-9321
dc.identifier.urihttp://hdl.handle.net/10400.1/14492
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.subjectBiological-activities
dc.subjectPhenolic composition
dc.subjectMulticomponent pattern
dc.subjectPlants
dc.subjectDecoctions
dc.subjectInfusions
dc.subjectProducts
dc.subjectWild
dc.subjectIngredients
dc.subjectCarvacrol
dc.titleUnravelling the potential of the medicinal halophyte Eryngium maritimum L.: In vitro inhibition of diabetes-related enzymes, antioxidant potential, polyphenolic profile and mineral composition
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04326%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F94407%2F2013/PT
oaire.citation.endPage212
oaire.citation.startPage204
oaire.citation.titleSouth African Journal of Botany
oaire.citation.volume120
oaire.fundingStream5876
oaire.fundingStreamSFRH
person.familyNameGuerreiro Pereira
person.familyNameRodrigues
person.familyNameCustódio
person.givenNameCatarina Alexandra
person.givenNameMaria João
person.givenNameLuísa
person.identifierNmxO5SIAAAAJ
person.identifierR-004-VNG
person.identifier.ciencia-id4512-3435-689C
person.identifier.ciencia-id2514-0E17-1D8D
person.identifier.ciencia-id791B-C560-AEA2
person.identifier.orcid0000-0002-1131-8773
person.identifier.orcid0000-0001-8732-710X
person.identifier.orcid0000-0003-4338-7703
person.identifier.ridM-6101-2013
person.identifier.scopus-author-id56031608100
person.identifier.scopus-author-id15831018900
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccess
rcaap.typearticle
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