Effect of warfarin in zebrafish (Danio rerio) bone formation during caudal fin regeneration

Dionísio, Gisela; Bensimon-Brito, A.; Gavaia, Paulo J.; Cancela, Leonor

http://hdl.handle.net/10400.1/4485

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Abstract(s)

In the last decade, fish has emerged as an important organism for studies on skeletal development in vertebrates, and evidence has been accumulated showing that zebrafish is a suitable system to perform phenotype-based drug screens. The ability to regenerate epidermal injuries is a general feature of most organisms yet only a few can fully regenerate severed appendages comprising several different tissues. Zebrafish is one of the most used models for regeneration studies, creating a powerful tool to study de novo bone formation without affecting vital development processes.

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http://hdl.handle.net/10400.1/4485

Citation

Dionísio G., Bensimon-Brito A., Gavaia P.J., Cancela M.L. 2009. Effect of warfarin in zebrafish (Danio rerio) bone formation during caudal fin regeneration. Interdisciplinary Approaches in Fish Skeletal Biology, April 27 – 29 Tavira, Portugal.