Ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate : synthesis and reactivity with dienes

Alves, Maria José Chão; Fortes, Gil; Lemos, A.; Martins, Cristina I.

http://hdl.handle.net/10400.1/1522

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Authors

Alves, Maria José Chão

Fortes, Gil

Lemos, A.

Martins, Cristina I.

Abstract(s)

Ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate, the first example of an 3-heteroamatic 2H-azirine has been prepared. The reaction of ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate with conjugated 1,3-dienes, under mild conditions and in the absence of Lewis acid catalyst, afforded cycloadducts in good yield and high stereoselectivity.