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Chitosan nanoparticles: a versatile platform for biomedical applications

2022-09-20Journal article Open access
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dc.contributor.authorBashir, Showkeen Muzamil
dc.contributor.authorAhmed Rather, Gulzar
dc.contributor.authorPatrício, Ana
dc.contributor.authorHaq, Zulfiqar
dc.contributor.authorSheikh, Amir Amin
dc.contributor.authorShah, Mohd Zahoor ul Haq
dc.contributor.authorSingh, Hemant
dc.contributor.authorKhan, Azmat Alam
dc.contributor.authorImtiyaz, Sofi
dc.contributor.authorAhmad, Sheikh Bilal
dc.contributor.authorNabi, Showket
dc.contributor.authorRakhshan, Rabia
dc.contributor.authorHassan, Saqib
dc.contributor.authorFonte, Pedro
dc.date.accessioned2022-10-14T10:02:28Z
dc.date.available2022-10-14T10:02:28Z
dc.date.issued2022-09-20
dc.date.updated2022-10-13T12:59:40Z
dc.description.abstractChitosan is a biodegradable and biocompatible natural polymer that has been extensively explored in recent decades. The Food and Drug Administration has approved chitosan for wound treatment and nutritional use. Furthermore, chitosan has paved the way for advancements in different biomedical applications including as a nanocarrier and tissue-engineering scaffold. Its antibacterial, antioxidant, and haemostatic properties make it an excellent option for wound dressings. Because of its hydrophilic nature, chitosan is an ideal starting material for biocompatible and biodegradable hydrogels. To suit specific application demands, chitosan can be combined with fillers, such as hydroxyapatite, to modify the mechanical characteristics of pH-sensitive hydrogels. Furthermore, the cationic characteristics of chitosan have made it a popular choice for gene delivery and cancer therapy. Thus, the use of chitosan nanoparticles in developing novel drug delivery systems has received special attention. This review aims to provide an overview of chitosan-based nanoparticles, focusing on their versatile properties and different applications in biomedical sciences and engineering.pt_PT
dc.description.sponsorshipPOCI-01-0145-FEDER-032610
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMaterials 15 (19): 6521 (2022)pt_PT
dc.identifier.doi10.3390/ma15196521pt_PT
dc.identifier.eissn1996-1944
dc.identifier.urihttp://hdl.handle.net/10400.1/18391
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationAlgarve Centre for Marine Sciences
dc.relationAlgarve Centre for Marine Sciences
dc.relationCentre for Marine and Environmental Research
dc.relationInstitute for Bioengineering and Biosciences
dc.relationInstitute for Bioengineering and Biosciences
dc.relationInstitute for Health and Bioeconomy
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectDrug deliverypt_PT
dc.subjectNanocarrierpt_PT
dc.subjectTarget therapypt_PT
dc.subjectChemotherapypt_PT
dc.subjectGene therapypt_PT
dc.subjectTssue engineeringpt_PT
dc.titleChitosan nanoparticles: a versatile platform for biomedical applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleAlgarve Centre for Marine Sciences
oaire.awardTitleCentre for Marine and Environmental Research
oaire.awardTitleInstitute for Bioengineering and Biosciences
oaire.awardTitleInstitute for Bioengineering and Biosciences
oaire.awardTitleInstitute for Health and Bioeconomy
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oaire.citation.issue19pt_PT
oaire.citation.startPage6521pt_PT
oaire.citation.titleMaterialspt_PT
oaire.citation.volume15pt_PT
oaire.fundingStream9471 - RIDTI
oaire.fundingStream6817 - DCRRNI ID
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person.familyNameFonte
person.givenNamePedro
person.identifier.ciencia-id2410-123D-3385
person.identifier.orcid0000-0002-1115-9282
person.identifier.ridK-3215-2013
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project.funder.nameFundação para a Ciência e a Tecnologia
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rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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