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In vitro biological activity screening of arbutus unedo leaves in light of their traditional use

2023-09Journal article Restricted
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dc.contributor.authorNunes, Ricardo
dc.contributor.authorSaraiva De Carvalho, Isabel
dc.contributor.authorPaśko, Paweł
dc.contributor.authorTyszka – Czochara, Małgorzata
dc.contributor.authorSzewczyk, Agnieszka
dc.contributor.authorSzlósarczyk, Marek
dc.contributor.authorPodolak, Irma
dc.contributor.authorGalanty, Agnieszka
dc.date.accessioned2023-11-06T14:41:39Z
dc.date.available2023-11-06T14:41:39Z
dc.date.issued2023-09
dc.description.abstractThe biological activity of A. unedo leaves, in relation to their traditional medicinal use in treating gastrointestinal and urinary tract diseases was verified. The ethanol extract of the leaves was quantitatively described in terms of flavonoids and phenolic acids (RP-HPLC), and zinc (voltametric analysis) and subjected to cytotoxic (MTT), antioxidant (TPC, TFC, TAA, RP, DPPH, and FRAP), antibacterial (disc diffusion), and antidiabetic assays (enzyme inhibition) in vitro. The extract was highly cytotoxic against prostate cancer cells, with less impact on colon carcinomas, while being nontoxic to normal prostate and kidney cells, and demonstrated antioxidant and antidiabetic activities.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1080/10496475.2023.2254284pt_PT
dc.identifier.eissn1540-3580
dc.identifier.urihttp://hdl.handle.net/10400.1/20128
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relationMICROMEDRONHO - DESIGNER DE MICROCÁPSULAS DE ARBUTUS UNEDO FOLHAS, FRUTOS E FLORES POR SPRAY DRYING PARA SUPLEMENTOS E ALIMENTOS FUNCIONAIS
dc.subjectAntioxidantpt_PT
dc.subjectAntidiabeticpt_PT
dc.subjectAntibacterialpt_PT
dc.subjectCytotoxicpt_PT
dc.titleIn vitro biological activity screening of arbutus unedo leaves in light of their traditional usept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMICROMEDRONHO - DESIGNER DE MICROCÁPSULAS DE ARBUTUS UNEDO FOLHAS, FRUTOS E FLORES POR SPRAY DRYING PARA SUPLEMENTOS E ALIMENTOS FUNCIONAIS
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBDE%2F51888%2F2012/PT
oaire.citation.endPage15pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleJournal of Herbs, Spices & Medicinal Plantspt_PT
person.familyNameNunes
person.familyNameSaraiva de Carvalho
person.givenNameRicardo
person.givenNameIsabel Maria Marques
person.identifier.ciencia-id591A-3777-B036
person.identifier.orcid0000-0003-4219-6788
person.identifier.orcid0000-0001-8057-3404
person.identifier.ridM-8563-2013
person.identifier.scopus-author-id35995183800
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication048f4226-0194-42aa-8b44-e25baf5f24b8
relation.isAuthorOfPublicationaf26e659-578b-4e5f-a649-384cd5e4f8e3
relation.isAuthorOfPublication.latestForDiscoveryaf26e659-578b-4e5f-a649-384cd5e4f8e3
relation.isProjectOfPublicationd46c1c6d-25cc-477e-a3d3-9b10e2d9e61a
relation.isProjectOfPublication.latestForDiscoveryd46c1c6d-25cc-477e-a3d3-9b10e2d9e61a

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