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Cortisol and parathyroid hormone-related peptide are reciprocally modulated by negative feedback

2006Journal article Restricted access
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dc.contributor.authorGuerreiro, P. M.
dc.contributor.authorRotllant, J.
dc.contributor.authorFuentes, J.
dc.contributor.authorPower, Deborah
dc.contributor.authorCanario, Adelino V. M.
dc.date.accessioned2014-05-09T09:14:52Z
dc.date.available2014-05-09T09:14:52Z
dc.date.issued2006
dc.date.updated2014-05-09T08:33:25Z
dc.description.abstractIn previous in vitro studies, we have shown that the N-terminal region of parathyroid hormone-related protein (PTHrP) can stimulate cortisol production in sea bream, Sparus auratus, interrenal tissue, possibly through a paracrine action. In the current study, the systemic interaction between cortisol and PTHrP was studied in vivo. Sustained elevated blood cortisol levels, induced either by cortisol injection or conWnement stress, suppressed circulating PTHrP 6 and 24-fold,respectively, by comparison to control Wsh.reduced cortisol levels, prevented the decrease of plasma PTHrP observed in conWned Wsh and raised plasma PTHrPrespectively, by comparison to control fish.por
dc.identifier.citationGuerreiro, Pedro M.; Rotllant, Josep; Fuentes, Juan; Power, Deborah M.; Canario, Adelino V.M.Cortisol and parathyroid hormone-related peptide are reciprocally modulated by negative feedback, General and Comparative Endocrinology, 148, 2, 227-235, 2006.por
dc.identifier.doi10.1016/j.ygcen.2006.03.004
dc.identifier.issn00166480
dc.identifier.urihttp://hdl.handle.net/10400.1/3815
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0016648006000773
dc.subjectParathyroid hormone-related peptidepor
dc.subjectCortisolpor
dc.subjectNegative feedbackpor
dc.subjectSea breampor
dc.subjectSparuspor
dc.titleCortisol and parathyroid hormone-related peptide are reciprocally modulated by negative feedbackpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage235por
oaire.citation.issue2por
oaire.citation.startPage227por
oaire.citation.titleGeneral and Comparative Endocrinologypor
oaire.citation.volume148por
person.familyNameGuerreiro da Costa Guerreiro
person.familyNameFuentes
person.familyNamePower
person.familyNameCanario
person.givenNamePedro Miguel
person.givenNameJuan
person.givenNameDeborah Mary
person.givenNameAdelino
person.identifierA-2539-2009
person.identifier392998
person.identifier143624
person.identifier.ciencia-id5C13-965D-3148
person.identifier.ciencia-id421B-E196-2C33
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.ciencia-id1F1E-D3B3-F804
person.identifier.orcid0000-0001-5371-7919
person.identifier.orcid0000-0003-0430-8734
person.identifier.orcid0000-0003-1366-0246
person.identifier.orcid0000-0002-6244-6468
person.identifier.ridC-7942-2009
person.identifier.scopus-author-id7201832526
person.identifier.scopus-author-id7101806760
person.identifier.scopus-author-id56568523700
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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relation.isAuthorOfPublicationd354b937-b18c-4ca5-a843-04a04269d60f
relation.isAuthorOfPublicationc68f5ffb-63f6-4c70-8957-29e464fb59c0
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relation.isAuthorOfPublication.latestForDiscoveryd0a8a148-98e7-4899-8fb0-0b8afa91e4a4

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