Publication
[4+2] Cycloadditions of 3-Tetrazolyl-1,2-diaza-1,3-butadienes: synthesis of 3-Tetrazolyl-1,4,5,6-tetrahydropyridazines
| dc.contributor.author | Lopes, Susana M. M. | |
| dc.contributor.author | Brigas, Amadeu | |
| dc.contributor.author | Palacios, Francisco | |
| dc.contributor.author | Lemos, A. | |
| dc.contributor.author | Melo, Teresa M. V. D. Pinho e | |
| dc.date.accessioned | 2012-04-18T15:32:49Z | |
| dc.date.available | 2012-04-18T15:32:49Z | |
| dc.date.issued | 2012 | |
| dc.date.updated | 2012-04-13T12:49:31Z | |
| dc.description.abstract | The synthesis of new 3-tetrazolyl-1,4,5,6-tetrahydropyridazines by Diels–Alder reactions of ethyl 3-(tetrazol-5-yl)-1,2- diaza-1,3-butadiene-1-carboxylates is reported. These 1,2- diaza-1,3-dienes reacted with electron-rich heterocycles, nucleophilic olefins and cumulenes, as well as with electrondeficient dienophiles, to give the target compounds regioselectively. Computational studies corroborated the rationalization of the observed reactivity and selectivity. | por |
| dc.identifier.citation | Lopes, Susana M. M.; Brigas, Amadeu F.; Palacios, Francisco; Lemos, A.; Melo, Teresa M. V. D. Pinho e. [4+2] Cycloadditions of 3-Tetrazolyl-1,2-diaza-1,3-butadienes: synthesis of 3-Tetrazolyl-1,4,5,6-tetrahydropyridazines. European Journal of Organic Chemistry, 2012, 11, 2152-2160, 2012. | por |
| dc.identifier.issn | 1434193X | |
| dc.identifier.other | AUT: ABR00608; ALE01411; | |
| dc.identifier.uri | http://hdl.handle.net/10400.1/1045 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.subject | Heterocycles | por |
| dc.subject | Aza-Diels-alder | por |
| dc.subject | Azoalkene | por |
| dc.subject | Pyridazine | por |
| dc.title | [4+2] Cycloadditions of 3-Tetrazolyl-1,2-diaza-1,3-butadienes: synthesis of 3-Tetrazolyl-1,4,5,6-tetrahydropyridazines | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 2160 | por |
| oaire.citation.issue | 11 | por |
| oaire.citation.startPage | 2152 | por |
| oaire.citation.title | European Journal of Organic Chemistry | por |
| person.familyName | Brigas | |
| person.familyName | Lemos | |
| person.givenName | Amadeu | |
| person.givenName | Americo | |
| person.identifier.ciencia-id | A81D-6DC7-31E4 | |
| person.identifier.orcid | 0000-0003-4875-4453 | |
| person.identifier.orcid | 0000-0001-9588-4555 | |
| person.identifier.rid | E-1897-2012 | |
| person.identifier.rid | B-4892-2008 | |
| person.identifier.scopus-author-id | 6701450565 | |
| person.identifier.scopus-author-id | 11139694000 | |
| rcaap.rights | restrictedAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | 7b0e903c-4730-497c-a012-f9fa0fc5e6dc | |
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| relation.isAuthorOfPublication.latestForDiscovery | 70dfe028-027a-4dec-b6e3-1a49c9be9e60 |