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Novel bioactive parathyroid hormone and related peptides in teleost fish

2006-01-09Journal article Restricted access
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dc.contributor.authorCanario, Adelino V. M.
dc.contributor.authorRotllant, J.
dc.contributor.authorFuentes, J.
dc.contributor.authorGuerreiro, P. M.
dc.contributor.authorTeodósio, H. R.
dc.contributor.authorPower, Deborah
dc.contributor.authorClark, M. S.
dc.date.accessioned2014-05-12T09:13:22Z
dc.date.available2014-05-12T09:13:22Z
dc.date.issued2006-01-09
dc.date.updated2014-05-09T08:36:22Z
dc.description.abstractWe report the identification, gene expression and biological activity of two parathyroid hormones (PTH; PTHA and PTHB), two PTH-related peptides (PTHrP; PTHrPA and PTHrPB) and a PTH-like ligand (PTH-L) with hybrid characteristics in puffer fishes (Takifugu rubripes and Tetraodon fluviatilis). Experimental data are consistent with PTH-L and PTHrPA having calciotropic activities equivalent, respectively, to tetrapod PTH and PTHrP. We hypothesise on the basis of phylogenetic and functional analysis that PTH-L could be a fish relic of an ancestral PTH/PTHrP gene.por
dc.identifier.citationCanario, A. V. M.; Rotllant, J.; Fuentes, J.; Guerreiro, P. M.; Teodosio, H. R.; Power, D. M.; Clark, M. S.Novel bioactive parathyroid hormone and related peptides in teleost fish, Febs Letters, 580, 1, 291-299, 2006.por
dc.identifier.doihttp://dx.doi.org/10.1016/j.febslet.2005.12.023
dc.identifier.issn0014-5793
dc.identifier.otherAUT: ACA00258; DPO00386;
dc.identifier.urihttp://hdl.handle.net/10400.1/3850
dc.language.isoengpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0014579305014845#por
dc.subjectParathyroid hormonepor
dc.subjectParathyroid hormone-related peptidepor
dc.subjectCalciotropicpor
dc.subjectReceptorpor
dc.subjectAdenylate cyclasepor
dc.subjectPhospholipase Cpor
dc.titleNovel bioactive parathyroid hormone and related peptides in teleost fishpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage299por
oaire.citation.issue1por
oaire.citation.startPage291por
oaire.citation.titleFebs Letterspor
oaire.citation.volume580por
person.familyNameCanario
person.familyNameFuentes
person.familyNameGuerreiro da Costa Guerreiro
person.familyNamePower
person.givenNameAdelino
person.givenNameJuan
person.givenNamePedro Miguel
person.givenNameDeborah Mary
person.identifier143624
person.identifier392998
person.identifierA-2539-2009
person.identifier.ciencia-id1F1E-D3B3-F804
person.identifier.ciencia-id421B-E196-2C33
person.identifier.ciencia-id5C13-965D-3148
person.identifier.ciencia-id891A-8A44-3CAE
person.identifier.orcid0000-0002-6244-6468
person.identifier.orcid0000-0003-0430-8734
person.identifier.orcid0000-0001-5371-7919
person.identifier.orcid0000-0003-1366-0246
person.identifier.ridC-7942-2009
person.identifier.scopus-author-id56568523700
person.identifier.scopus-author-id7201832526
person.identifier.scopus-author-id7101806760
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication5f6e51ee-9113-469e-8b9e-f30f2d452521
relation.isAuthorOfPublicationd354b937-b18c-4ca5-a843-04a04269d60f
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relation.isAuthorOfPublicationc68f5ffb-63f6-4c70-8957-29e464fb59c0
relation.isAuthorOfPublication.latestForDiscovery5f6e51ee-9113-469e-8b9e-f30f2d452521

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