Polyoxovanadates contribution to pharmacological, antimicrobial and toxicological actions of vanadium

Fraqueza, Gil; Aureliano, Manuel

http://hdl.handle.net/10400.1/28276

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Autores

Fraqueza, Gil

Aureliano, Manuel

Resumo(s)

Studies of the pharmacological action of vanadium compounds have shown that vanadium has been arousing interest as a potential candidate for therapeutic applications. Polyoxovanadates (POVs) emerge from polyoxometalatates (POMs) and are responsible for an increase in the number of vanadium studies on multidirectional biological activity in view of their application in biomedicine. In fact, increasing research studies have shown POVs’ anti-bacterial, anti-fungal, anti-parasitic, anti-viral, anti-cancer as well as anti-diabetic activities. Herein, we highlight decavanadate and decavanadate compounds, perhaps the most studied POVs in biology, strengthening the potential use of such metallodrugs in the future. Thus, vanadium compounds, including POVs, show a great potential in the treatment of many types of diseases.