Illumination correction and analysis of two-dimensional microscopy images of Loa loa microfilariae

Al-Tam, Faroq

Publication

Illumination correction and analysis of two-dimensional microscopy images of Loa loa microfilariae

2016-07-06Doctoral thesis

datacite.subject.fos	Engenharia e Tecnologia::Engenharia Eletrotécnica, Eletrónica e Informática	pt_PT
dc.contributor.advisor	Shahbazkia, Hamid Reza
dc.contributor.advisor	Anjos, António dos
dc.contributor.author	Al-Tam, Faroq
dc.date.accessioned	2018-09-14T10:38:37Z
dc.date.available	2018-09-14T10:38:37Z
dc.date.issued	2016-07-06
dc.date.submitted	2016
dc.description.abstract	This thesis addresses the problem of detecting a common parasitic micro laria that causes loaisis, a major disease problem in Central and Western Africa. The dose of medicine to be administered to the patient is proportional to the estimated number of micro lariae in the patient's body. Therefore, proper estimation of the number of micro lariae is the key for conducting the right procedure. The clinical examination is necessary to estimate the micro lariae density in a blood sample drawn from the patient. Thereafter, visual inspection of the sample is performed. The main challenge in this work is, however, the development of an automatic detection system of micro lariae in 2-D images. Such problem is new in the image processing literature, and the development of such system is very important for performing better diagnosis and treatment of this disease and other similar diseases. A comprehensive review of, both generic and thin, object detectors in 2-D images is presented. A very robust method for microscopy image illumination correction is proposed, and a new powerful descriptor, the Hessian-Polar Context (HPC), for micro lariae is also introduced. These are then combined in a micro lariae detection system, where a simple, yet e cient, hypotheses generator is also presented. Additionally, several methods and applications for di erent image modalities are proposed. These involve a method and an application for the analysis of rice panicle in 2-D images. Additionally, an e cient method for artifact suppression in X-ray image is also proposed. The proposed methods are compared to a set of state-of-the-art methods. Experimental results show that the developed methods are great contributions to the microscopy and X-ray imaging elds.	pt_PT
dc.identifier.tid	101374674	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.1/10795
dc.language.iso	eng	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Illumination correction	pt_PT
dc.subject	Loa loa microfilariae	pt_PT
dc.subject	Two-dimensional microscopy images	pt_PT
dc.title	Illumination correction and analysis of two-dimensional microscopy images of Loa loa microfilariae	pt_PT
dc.type	doctoral thesis
dspace.entity.type	Publication
person.familyName	Al-Tam
person.givenName	Faroq
person.identifier	R-00G-A33
person.identifier.ciencia-id	2515-AFE3-525F
person.identifier.orcid	0000-0001-9718-2039
person.identifier.rid	K-7031-2016
person.identifier.scopus-author-id	55246034700
rcaap.rights	openAccess	pt_PT
rcaap.type	doctoralThesis	pt_PT
relation.isAuthorOfPublication	15ac97f4-a867-462d-9fc6-0a47bb2919d3
relation.isAuthorOfPublication.latestForDiscovery	15ac97f4-a867-462d-9fc6-0a47bb2919d3
thesis.degree.grantor	Universidade do Algarve. Faculdade de Ciências e Tecnologia
thesis.degree.level	Doutor
thesis.degree.name	Doutoramento em Engenharia Informática	pt_PT