Repository logo
 
Publication

Comparing the diagnostic performance of ultrasound elastography and magnetic resonance imaging to differentiate benign and malignant breast lesions: a systematic review and meta-analysis

2025-08Journal article Restricted access
Simple item page
dc.contributor.authorGomes, Ana Filipa
dc.contributor.authorJustino, David
dc.contributor.authorTomás, Carina
dc.contributor.authorJesus, Diogo
dc.contributor.authorMacedo, Ana
dc.contributor.authorPinto, Ezequiel
dc.contributor.authorLeitao, Helena
dc.date.accessioned2025-10-09T10:14:44Z
dc.date.available2025-10-09T10:14:44Z
dc.date.issued2025-08
dc.description.abstractObjective: The purpose of this systematic review and meta-analysis was comparing diagnostic performance of ultrasound elastography (UE), strain UE and shear wave elastography (SWE), with magnetic resonance imaging (MRI) in differentiating benign and malignant breast lesions. Methods: Literature search of MEDLINE, Web of Science, SCOPUS and Google Scholar was performed in June 2023. Included studies used Breast Imaging Reporting and Data System (BI-RADS) and histopathology as reference standard. A bivariate random-effects model was used to calculate sensitivity, specificity, diagnostic odds ratio (DOR), positive and negative likelihood ratios and area under the curve (AUC). Meta-regression subgroup analysis was performed. Results: Nine studies and 536 lesions were included. Pooled sensitivity was not different between MRI vs UE [MRI: 94% (95% CI: 88.2%-96.9%) vs UE: 90% (95% CI: 84.7%-93.1%); P=0.153] but a difference was found for specificity [UE: 78% (95% CI: 66.3%-86.4%) vs MRI: 71.3% (95% CI: 52.1%-85%); P=0.0065]. Strain UE showed higher specificity and similar sensitivity to SWE [strain UE: 0.85 (95% CI: 0.71-0.93) vs SWE: 0.72 (95% 0.58-0.83); P=0.017 and strain UE: 0.87 (95% CI 0.79-0.93) vs SWE: 0.91 (95% CI 0.85-0.95); P=0.311, respectively]. AUC was similar between MRI vs UE [0.91 (95% CI 0.87-0.95) vs 0.92 (95% CI 0.88-0.95); P=0.452, respectively] as was DOR [MRI: 38.083 (95% CI: 12.401-116.957) vs UE: 30.395 (95% CI: 16.572-55.75); P > 0.05]. Meta-regression analysis found no significant differences in the diagnostic accuracy between MRI, strain UE and SWE. Conclusion: Our results show that UE when compared to MRI has adequate performance in differentiating benign and malignant breast lesions.eng
dc.identifier.doi10.1016/j.acra.2024.12.061
dc.identifier.issn1076-6332
dc.identifier.urihttp://hdl.handle.net/10400.1/27809
dc.language.isoeng
dc.peerreviewedyes
dc.publisherThe Association of Academic Radiology
dc.relation.ispartofAcademic Radiology
dc.rights.uriN/A
dc.subjectBreast tumors
dc.subjectMagnetic resonance imaging
dc.subjectUltrasound
dc.subjectElastography
dc.titleComparing the diagnostic performance of ultrasound elastography and magnetic resonance imaging to differentiate benign and malignant breast lesions: a systematic review and meta-analysiseng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue8
oaire.citation.titleAcademic Radiology
oaire.citation.volume32
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameGomes
person.familyNameMacedo
person.familyNamePinto
person.familyNameLeitao
person.givenNameAna Filipa
person.givenNameAna
person.givenNameEzequiel
person.givenNameHelena
person.identifier.ciencia-id8414-F029-8182
person.identifier.ciencia-idB51E-381F-63B5
person.identifier.orcid0009-0006-9071-9239
person.identifier.orcid0000-0002-6978-8989
person.identifier.orcid0000-0001-9322-2937
person.identifier.orcid0000-0001-6596-2671
person.identifier.ridL-9912-2018
relation.isAuthorOfPublication2cfd18ee-317c-49f6-9f13-8e045367cfe0
relation.isAuthorOfPublication8e798bcb-5052-47b0-a050-32f40328cc1a
relation.isAuthorOfPublication9e56ecbb-6cca-45e4-ac9f-9a736c13d793
relation.isAuthorOfPublicationbd31b91a-928e-4c4a-a2b5-c588ade3e998
relation.isAuthorOfPublication.latestForDiscovery8e798bcb-5052-47b0-a050-32f40328cc1a

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
1-s2.0-S1076633224010493-main.pdf
Size:
3.09 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.46 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

FCB2-Artigos (em revistas ou actas indexadas)
ABC2-Artigos (em revistas ou actas indexadas)
ESS2-Artigos (em revistas ou actas indexadas)